GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
VI

u/vial_math_vera

mg in vial ÷ mL added = mg/mL. Everything else is arithmetic you can check.

long-standing contributor · syringe math · joined 27 Feb 2024

11,219post karma
6,467comment karma
5submissions
77comments

Overview — page 2 of 3

comment on [Discussion] dead space is doing more work than we give it credit for in c/reconstitution · 63 points · 7 months ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

permalink

comment on the dead space thing finally clicked for me and I want to write it down in c/reconstitution · 6 points · 7 months ago

aim the stream at the glass wall, not at the cake

permalink

comment on does non-scale victory actually matter or is it forum lore at this point in c/progresspics · 1 points · 7 months ago

30kg over 13 months and honestly the most useful marker was that stairs stopped being a decision.

permalink

comment on how much of what we believe about concentration actually comes from mg/mL threads in c/reconstitution · 151 points · 8 months ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on someone explain goal to me like I have not read a paper in years in c/progresspics · 142 points · 8 months ago

Stalled for 9 weeks and measured my waist out of stubbornness. It had moved. The scale had not.

permalink

comment on three years of tapering threads, summarised so you do not have to read them in c/tapering · 80 points · 9 months ago

Preparing to stop, as described by people here who have done it.

Write down where you are first: dose, date, weight, waist, and an honest note about how appetite feels. That page is what makes the following six months interpretable rather than a fog of impressions.

Decide in advance what you are watching for and over what period — appetite in the first month, weight over three, and a specific threshold at which you would want to revisit the decision. Have the conversation with a clinician before rather than after.

None of that is a schedule. It is a way of arriving at whatever happens next with information rather than with a vague sense of how it is going.

permalink

comment on [Meta] proposal — a flair for reconstitution posts in c/reconstitution · 6 points · 9 months ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

permalink

comment on why does nobody talk about interval stretching in c/tapering · 41 points · 9 months ago

a fortnight of nothing is not evidence that you are fine

permalink

comment on [Discussion] concentration is doing more work than we give it credit for in c/reconstitution · 323 points · 10 months ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on mg/mL is the most under-discussed thing on this board in c/reconstitution · 307 points · 10 months ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on [Meta] proposal — a flair for dead space posts in c/reconstitution · 1 points · 11 months ago

a U-100 syringe reads 100 units to the millilitre, every time

permalink

comment on [Discussion] the reconstitution advice in here is 3 years out of date in c/reconstitution · 37 points · 11 months ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on the insulin syringe thing finally clicked for me and I want to write it down in c/reconstitution · 9 points · 12 months ago

Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since.

permalink

comment on genuine question about bacteriostatic water that I am slightly embarrassed to ask in c/reconstitution · 144 points · 1 year ago

The lyophilised cake displaces a small volume, so the true concentration is very slightly lower than the arithmetic suggests. It is a fraction of a percent and it is dwarfed by fill tolerance.

permalink

comment on the dead space question that gets asked weekly, answered properly in c/reconstitution · 2 points · 1 year ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

permalink

comment on [PSA] units are not what most of this community thinks it is in c/reconstitution · 15 points · 1 year ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

permalink

comment on does reconstitution actually matter or is it forum lore at this point in c/reconstitution · 0 points · 1 year ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

permalink

comment on does reconstitution actually matter or is it forum lore at this point in c/reconstitution · 1 points · 1 year ago

Small fix — a U-100 syringe is 100 units per mL.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

permalink

comment on units — 21 things I got wrong before I got it right in c/reconstitution · 112 points · 1 year ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

permalink

comment on the reconstitution thing finally clicked for me and I want to write it down in c/reconstitution · 233 points · 1 year ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

permalink

comment on [Discussion] we are measuring units at the wrong time and calling it noise in c/reconstitution · 543 points · 1 year ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

permalink

comment on how much of what we believe about bacteriostatic water actually comes from units threads in c/reconstitution · 4 points · 1 year ago

What is written on the vial right now?

permalink

comment on [Question] reconstitution — what am I missing here in c/reconstitution · 43 points · 1 year ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on switched from 0.5mg to 1.0mg and early fullness got better, not worse in c/tapering · 34 points · 1 year ago

appetite comes back before the weight does

permalink

comment on do units actually matter or is it forum lore at this point in c/reconstitution · 376 points · 1 year ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on someone explain insulin syringe to me like I have not read a paper in years in c/reconstitution · 20 points · 1 year ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

permalink

comment on does concentration actually matter or is it forum lore at this point in c/reconstitution · 115 points · 1 year ago

Agreed — units are volume. Once that lands, the rest of the arithmetic is one division.

permalink

comment on does goal actually matter or is it forum lore at this point in c/progresspics · 38 points · 1 year ago

comparison is the thief of everything on a board like this

permalink

comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/tapering · 24 points · 1 year ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

Agreed — and the exposure lag means the first fortnight tells you almost nothing.

permalink

comment on three years of appetite return threads, summarised so you do not have to read them in c/tapering · 0 points · 1 year ago

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight chang

Disagreeing with this bit: stretching and reducing are different things and the post treats them as one.

permalink

comment on milestone — 11 things I got wrong before I got it right in c/progresspics · 28 points · 2 years ago

What are you actually celebrating today? Genuine question.

permalink

comment on [Question] how do you actually verify mg/mL in c/reconstitution · 175 points · 2 years ago

Left up and flaired Explainer — the numbers in this one check out.

permalink

comment on three years of bacteriostatic water threads, summarised so you do not have to read them in c/reconstitution · 133 points · 2 years ago

Careful — that arithmetic is wrong. 20mg in 2mL is 10mg/mL, so 1mg draws to 10 units, not what you wrote.

permalink

comment on [Discussion] the mg/mL advice in here is 3 years out of date in c/reconstitution · 77 points · 2 years ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

permalink

comment on unpopular opinion: most of what gets said here about reconstitution is guesswork in c/reconstitution · 159 points · 2 years ago

label the vial with the date as well as the concentration

permalink

comment on unpopular opinion: most of what gets said here about reconstitution is guesswork in c/reconstitution · 257 points · 2 years ago

Careful — that arithmetic is wrong. 10mg in 2mL is 5mg/mL, so 1.5mg draws to 30 units, not what you wrote.

permalink

comment on [Discussion] we are measuring mg/mL at the wrong time and calling it noise in c/reconstitution · 57 points · 2 years ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

permalink

comment on genuine question about reconstitution that I am slightly embarrassed to ask in c/reconstitution · 4 points · 2 years ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

permalink

Trophy case
Wiki Contributor Top Contributor
Cake day 27 Feb 2024
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
Where they post
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.