c/t2dglp1 · created 13 Jun 2024
Glycaemic control first. A1c, CGM, and stacking with metformin.
A1c 9.1 → 5.4, full table, 14 months. Posting the boring middle of the process, because the internet is full of the start and the end and nothing else. Figures up front…
stacking with a sulfonylurea is a real hypo risk, not a theoretical one, which sounds obvious until you try to state the evidence for it. Certain conditions affect A1c…
metformin alongside — keep it or drop it. I am not trying to be the "source?" guy. I would just like a source. Panicked over a first-day sensor reading and rebuilt my…
my dawn phenomenon barely changed and that surprised me. Not a hot take, just something I have not seen said plainly here. Kept fingersticks alongside the sensor for…
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardsthe weight conversation drowns out the glycaemic one — a position I have arrived at slowly and would like tested. The order things move in, since nobody explains it and…
A1c 5.6 but CGM says otherwise. which do i believe. I would rather ask a basic question now than get this wrong quietly for two months. Postprandial excursions…
is it normal to get early fullness at week 88, logged the same way every week so the comparison is at least internally fair. Postprandial excursions typically respond…
unpopular opinion: most of what gets said here about hypoglycaemia is guesswork. Not a hot take, just something I have not seen said plainly here. Postprandial…
37 weeks on 15mg, full numbers, ask me anything boring. This is a description of what happened to me and not a plan for anybody else. To save the first four comments:…
Writing this once so it can be linked instead of retyped: hypoglycaemia is not what most of this community thinks it is. Assumed the weight endpoints from the obesity…
Something I keep coming back to: the hypoglycaemia question that gets asked weekly, answered properly. My A1c moved and it turned out to have nothing to do with glucose…
Reporting in. 24 months in and metformin is still the thing I get wrong. 24 months. Those are measured, not estimated, and not rounded up in my favour. My ApoB moved…
Genuine question, and the title is the question: why does nobody talk about A1c. My TSH moved and it turned out to have nothing to do with glucose at all. Variability…
help me understand T2D, I have read the wiki twice. I am not trying to be the "source?" guy. I would just like a source. Postprandial excursions typically respond…
Slightly embarrassed to be asking this, but: someone explain glycaemic control to me like I have not read a paper in years. Time in range told me far more than the…
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
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glbiochem.netthe hypoglycaemia rule is doing its job and people should stop complaining. Nothing about this affects the ranking maths, before anyone asks. The diabetes and obesity…
The title is the argument: tried glycaemic control for 4 weeks. here is what happened. Here is the rest of it. Since the title puts numbers in the shop window: 4 weeks.…
Reporting in. anyone else notice T2D kicking in around week 89. On hypoglycaemia, because the risk gets attributed to the wrong thing constantly. Incretin-based agents…
Something I keep coming back to: unpopular opinion: most of what gets said here about glycaemic control is guesswork. Time in range told me far more than the average…
why does nobody talk about CGM — that is what I am asking, and I have already read the wiki twice. Assumed the weight endpoints from the obesity trials applied to my…
Trying to get a straight answer on this: how much of what we believe about A1c actually comes from glycaemic control threads. Brought the whole CGM export to my…
three years of T2D threads, summarised so you do not have to read them. I have gone back and forth on this for months. Panicked over a first-day sensor reading and…
Slightly embarrassed to be asking this, but: how do you actually verify glycaemic control. My A1c moved and it turned out to have nothing to do with glucose at all. The…
how do you actually verify A1c — that is what I am asking, and I have already read the wiki twice. Assumed the weight endpoints from the obesity trials applied to my…
Trying to get a straight answer on this: genuine question about A1c that I am slightly embarrassed to ask. Sensor accuracy varies across wear, and readings on the first…
Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.
Certified reference materials for peptide identity and purity work.
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