is it normal to get early fullness at week 88
is it normal to get early fullness at week 88, logged the same way every week so the comparison is at least internally fair.
Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.
A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.
Screenshot none of this. Read the whole thread, including the parts where I am told I am wrong.
best — the order this archive was captured in
Incretin-based agents stimulate insulin secretion in a glucose-dependent manner, which is why hypoglycaemia risk with them alone is low. Risk rises with agents that act independently of glycaemia.
Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.
Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.
Disagree — that is an obesity trial endpoint and this thread is about glycaemic control.
The diabetes and obesity programmes are separate, with different populations and different primary endpoints. Reading a result across from one to the other is not a comparison.
Right, and the diabetes programmes report glycaemic endpoints. Quoting an obesity trial result here is answering a different question.
nothing here replaces the person managing your diabetes
Retitled — the original quoted an obesity endpoint as a glycaemic one.
That A1c change is inside the assay’s variability and the interval you measured over is too short.
This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.
Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.
sensor accuracy varies and the first day of a sensor is the worst
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metformin and an incretin agonist are not in competition
Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.
Certain conditions affect A1c independently of glycaemia.
Agreed, and the glucose-dependence point is the reason the risk profile reads the way it does.
Agreed on variability. Two people with the same average can have completely different days.
I would not compare your numbers to that population. Different baseline, different regimen, different trial.
- 1Right, and the diabetes programmes report glycaemic endpoints. Quoting an…11 comments in this branch · started by u/freya_onwuka