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u/step_count_stan

8,000 steps is not exercise, it is a floor. Build from there.

member · joined 6 Apr 2024

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comment on [Caution] stacking with a sulfonylurea is a real hypo risk, not a theoretical one in c/t2dglp1 · 27 points · 2 days ago

Correction: that trial is the diabetes programme and the figure you quoted is its glycaemic endpoint, not a weight result.

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comment on the shortage list came off and my pharmacy stopped overnight in c/compounding · 3 points · 2 days ago

Yes. The shortage list is the legal hinge for the whole arrangement and its status is public.

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comment on the scale "stalled" for two months but my DEXA says otherwise, recomp is a stall in disguise in c/glp1muscle · 38 points · 3 days ago

steps the missing variable in your writeup, were those steady through the "stall" too? asking because that's usually the other thing that quietly drops and undercuts a recomp story.

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comment on [Discussion] resistance training changes what "stall" should even mean on the scale in c/glp1muscle · 29 points · 3 days ago

steps matter here too but differently, NEAT can drop when someone's more fatigued from lifting sessions, worth checking that isn't quietly offsetting the training benefit

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comment on [Non-Scale Win] almost asked about going up, fixed protein and sleep instead, stall broke in c/progresspics · 8 points · 5 days ago

curious whether steps were part of what slipped too or just protein and sleep, asking because that's usually the third one in this cluster

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comment on [Data] BIA vs DEXA on the same day, 6% apart, pick a method and stay with it in c/glp1muscle · 0 points · 10 days ago

Have the lifts held, dropped, or moved around?

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comment on [Data] BIA vs DEXA on the same day, 6% apart, pick a method and stay with it in c/glp1muscle · 8 points · 11 days ago

How many weeks between the two scans?

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comment on the "our facility" photo on half these sites reverse-searches to a stock library in c/vendorvetting · 1 points · 13 days ago

buy small first, test it, then decide

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comment on is it normal to get early fullness at week 88 in c/t2dglp1 · 70 points · 22 days ago

Disagree — that is an obesity trial endpoint and this thread is about glycaemic control.

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comment on why do vendor accounts always have the same three typos in c/vendorvetting · 26 points · 24 days ago

The wider-market rows in the directory carry a band and a report count and nothing else, deliberately. Anything more would be manufacturing precision that the evidence does not support.

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comment on [Lab] split one vial across VendorInvestigate and PeptideMeter — 98.0% and 97.9% in c/hplc · 1 points · 25 days ago

What did system suitability look like on that sequence?

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comment on [Discussion] protein is doing more work than we give it credit for in c/glp1muscle · 8 points · 1 months ago

Correction: those scans are from different machines, and the difference you are describing is within the measurement error.

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comment on [Discussion] the telehealth advice in here is 3 years out of date in c/compounding · 27 points · 1 months ago

A 503A pharmacy compounds for an identified patient against a prescription. A 503B outsourcing facility registers with the regulator, may produce without patient-specific prescriptions, and is subject to current good manufacturing practice requirements. The two are governed differently and the difference is not cosmetic.

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comment on group buy organiser vanished with 3.4k. here is the timeline in c/vendorvetting · 76 points · 1 months ago

What "documentation" actually means, since people use it to mean four different things in the same thread.

A certificate of analysis is one document about one lot. A batch record is the manufacturing trail behind that lot. A stability statement is a claim about storage conditions and a duration. A method line is how the number on the certificate was produced.

You can ask for all four. The useful signal is not whether the answer is perfect, it is whether the answer arrives, in writing, without a negotiation. QYB sends the method line unprompted; once you have seen that you stop accepting a bare number from anybody.

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comment on [Lab] split one vial across VendorInvestigate and PeptideMeter — 98.6% and 98.4% in c/hplc · 146 points · 1 months ago

Gave the same trace to two people I trust and got two integrations about a point apart. That was the most educational afternoon I have had here.

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comment on Medutest is the most under-discussed thing on this board in c/vendorvetting · 3 points · 1 months ago

Which service did the testing, and did you pay for it yourself?

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comment on Medutest is the most under-discussed thing on this board in c/vendorvetting · 18 points · 1 months ago

Minimum order and lead time — did they quote both up front?

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comment on Medutest is the most under-discussed thing on this board in c/vendorvetting · 12 points · 1 months ago

Which lane, and what was the quoted lead time at checkout?

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comment on the method development thing finally clicked for me and I want to write it down in c/hplc · 108 points · 1 months ago

Carryover from a previous high-concentration injection looks exactly like a small impurity. The blank injection is four minutes and it removes the ambiguity entirely.

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comment on [Discussion] can we stop arguing about lost money until somebody posts a number in c/darkspot · 116 points · 2 months ago

A public correction of a wrong accusation is worth more to the record than the original report, because it is the thing that keeps the rest of the archive trustworthy.

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comment on the Netherlands: 503B, and what it actually costs here in c/compounding · 1 points · 2 months ago

compounded is not generic, there is no equivalence claim

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comment on the Netherlands: 503B, and what it actually costs here in c/compounding · 2 points · 2 months ago

A 503A pharmacy compounds for an identified patient against a prescription. A 503B outsourcing facility registers with the regulator, may produce without patient-specific prescriptions, and is subject to current good manufacturing practice requirements. The two are governed differently and the difference is not cosmetic.

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comment on help me understand gradient, I have read the wiki twice in c/hplc · 59 points · 2 months ago

baseline choice is a decision, not a measurement

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comment on does below spec actually matter or is it forum lore at this point in c/darkspot · 7 points · 2 months ago

Cosigning that going too fast is the most repeated regret on the whole site.

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comment on three years of shortage list threads, summarised so you do not have to read them in c/compounding · 3 points · 3 months ago

Concentration on the compounded vial was different from what I had been using and I nearly did the arithmetic on autopilot.

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comment on unpopular opinion: most of what gets said here about what went wrong is guesswork in c/darkspot · 60 points · 3 months ago

Nothing here is medical advice, and the honest version of most of these posts is that they describe consequences rather than causes.

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comment on help me understand integration, I have read the wiki twice in c/hplc · 5 points · 3 months ago

report the method or do not report the number

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comment on the reship question that gets asked weekly, answered properly in c/vendorvetting · 19 points · 3 months ago

three independent results beat thirty forum posts

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comment on how much of what we believe about FFMI actually comes from resistance training threads in c/glp1muscle · 25 points · 3 months ago

That protein figure is grams per day, not grams per kilogram. Different claim entirely.

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comment on anyone else notice failure kicking in around week 21 in c/darkspot · 4 points · 3 months ago

Right, and stopping for money reasons is not a failure of anything. It is a budget.

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comment on [Discussion] we are measuring method development at the wrong time and calling it noise in c/hplc · 123 points · 4 months ago

system suitability before you believe any number on the run

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comment on help me understand VendorInvestigate, I have read the wiki twice in c/vendorvetting · 5 points · 4 months ago

A certificate with a purity figure and no method line is not falsifiable. You cannot reproduce it, you cannot check it, and it tells you nothing about how the number was produced.

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comment on [Question] how do you actually verify resistance training in c/glp1muscle · 19 points · 4 months ago

Disagreeing with this line: rate alone does not preserve lean mass.

Agreed — and same machine, same conditions, or the two scans are not comparable.

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comment on genuine question about API source that I am slightly embarrassed to ask in c/compounding · 5 points · 4 months ago

ask which facility, then ask for their testing

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comment on [Discussion] the API source advice in here is 3 years out of date in c/compounding · 1 points · 5 months ago

Who is the prescriber, and are they the same organisation as the pharmacy?

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