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c/t2dglp1·submitted 23 days ago by u/camila_vasquez

is it normal to get early fullness at week 88

Cautionbranch of 11 comments

is it normal to get early fullness at week 88, logged the same way every week so the comparison is at least internally fair. Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working. A1c reflects average glycaemia over roughly…

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11 comments, started 22 days ago
u/freya_onwuka31 points·22 days ago

Right, and the diabetes programmes report glycaemic endpoints. Quoting an obesity trial result here is answering a different question.

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u/lyophile_lou10 points·21 days ago

nothing here replaces the person managing your diabetes

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u/a1c_arcMOD19 points·21 days ago

Retitled — the original quoted an obesity endpoint as a glycaemic one.

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u/milan_chukwu13 points·21 days ago

That A1c change is inside the assay’s variability and the interval you measured over is too short.

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u/santiago_rasmussen4 points·21 days ago

This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.

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u/cormac_danquah19 points·21 days ago

Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.

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u/thandi_solberg8 points·21 days ago

sensor accuracy varies and the first day of a sensor is the worst

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[removed]8 points·21 days ago

[removed by moderator]

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u/bianca_demir2 points·21 days ago

metformin and an incretin agonist are not in competition

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u/stablecoin_steve13 points·21 days ago

Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.

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u/gentle_correctionnice about it9 points·21 days ago

Certain conditions affect A1c independently of glycaemia.

Agreed, and the glucose-dependence point is the reason the risk profile reads the way it does.

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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