[Results] 83 weeks, 13kg, and CGM was the hard part
Update, and the title has the headline: 83 weeks, 13kg, and CGM was the hard part.
The numbers the title promised, since a headline without them is worthless: 83 weeks and 13kg. Everything below is context for those.
Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.
The diabetes and obesity programmes are separate, with different populations and different primary endpoints. Reading a result across from one to the other is not a comparison.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
best — the order this archive was captured in
Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.
Identifying details redacted from the exported report above.
Assumed the weight endpoints from the obesity trials applied to my situation. They are different programmes.
This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.
Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.
nothing here replaces the person managing your diabetes
Agreed on variability. Two people with the same average can have completely different days.
Disagree — that is an obesity trial endpoint and this thread is about glycaemic control.
A1c, CGM, or fingersticks — which are we discussing?
A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.
Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.
Not convinced. Hypoglycaemia risk from this class alone is low; the risk you are describing comes from the combination.
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postprandial excursions are where most of the improvement shows up first
My triglycerides moved and it turned out to have nothing to do with glucose at all.
Agreed. A1c is an integrated average over roughly three months and treating it as a current reading causes a lot of unnecessary alarm.
Push back: one sensor reading is not a data point worth acting on, especially in the first day of wear.
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