SURPASS

Thinking out loud about this: SURPASS — 12 things I got wrong before I got it right. Started keeping the trial identifiers straight in a note file because I kept mixing…

Something I keep coming back to: the Mounjaro thing finally clicked for me and I want to write it down. Week 47 was the first time the scale moved after a five-week…

SURPASS — 4 things I got wrong before I got it right. Change my mind, genuinely — I have no stake in being right about this. The registered protocol is public.…

the FLOW rule is doing its job and people should stop complaining. This affects how posts get sorted and removed, so it belongs in the open. The discontinuation numbers…

The title is the argument: compounded tirz pricing has doubled in my area in four months. Here is the rest of it. The distribution matters more than the mean. In the…

how do you actually verify SURPASS. I would rather ask a basic question now than get this wrong quietly for two months. The discontinuation numbers were the most useful…

Asking properly rather than in a comment on somebody else’s thread: why does nobody talk about SELECT. Compared myself to a trial mean for about six months before…

the Zepbound question that gets asked weekly, answered properly, and I am aware this is a minority view on this board. Sulphur burps for the first eight days after each…

Thinking out loud about this: Mounjaro is the most under-discussed thing on this board. Switching from semaglutide, since three people asked in this thread alone. There…

Posting this because the title is the whole finding — split one vial across PeptideMeter and VendorInvestigate — 98.4% and 97.2% — and a number without its method is a…

small win: dual agonist stopped being a problem at week 50, and the part I actually want to talk about is at the bottom. Week 7 was the first time the scale moved after…

Asking properly rather than in a comment on somebody else’s thread: why does nobody talk about SELECT. Relative risk reduction without the baseline rate is…

The title is the whole question — am I the only one who found Mounjaro harder than the injections — but here is why I am asking. The thing nobody warned me about was…

Putting this at the top of the board where it belongs: Zepbound is not what most of this community thinks it is. The four-week interval in the label is a minimum.…

Posting this as a discussion rather than a claim: the GIP question that gets asked weekly, answered properly. Vials and pens carry the same molecule; what differs is…

Right: is 93.7% actually fine or am I being sold a rounding error. I paid for this one myself, nobody sent me anything, and the receipts are in the comments. The…

why does nobody talk about SELECT. Searched first, found three threads that contradict each other, hence the post. Spent an evening with the appendix tables and found…

Explainer, as requested in the last thread: GIP is not what most of this community thinks it is. Vials and pens carry the same molecule; what differs is fill volume,…

how much of what we believe about endpoint actually comes from TRIUMPH threads. I would rather ask a basic question now than get this wrong quietly for two months. A…

SURPASS — 12 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Relative risk reduction without the baseline rate is…

someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial…

GIP agonism explained like i am five, please — a position I have arrived at slowly and would like tested. Vials and pens carry the same molecule; what differs is fill…

the endpoint advice in here is 3 years out of date. It is the sort of thing everyone half-believes and nobody writes down. 3 years. Those are measured, not estimated,…

Asking properly rather than in a comment on somebody else’s thread: how do you actually verify GIP. Vials and pens carry the same molecule; what differs is fill volume,…

The title is the whole question — help me understand SURMOUNT, I have read the wiki twice — but here is why I am asking. Discontinuation rates are a tolerability…