compounded tirz pricing has doubled in my area in four months
The title is the argument: compounded tirz pricing has doubled in my area in four months. Here is the rest of it.
The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.
Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.
Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate.
Would rather be corrected in public than confident in private.
best — the order this archive was captured in
The four-week interval in the label is a minimum. Nothing about the pharmacology requires you to step on schedule, and the trials stepped on a calendar because trials have to.
What is the waist doing? That is usually the number still moving during a scale stall.
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.
hold the dose that works, the ladder is not a leaderboard
pens and vials are the same molecule, the price is the difference
SURMOUNT-1 landed around 21% at 72 weeks on the top arm
Does injection-site soreness follow the day after the shot, or is it spread across the week?
sulphur burps are the signature complaint and they are not dangerous
zepbound and mounjaro are the same compound with different labels
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
the appetite effect is blunter than sema, in a good way, most weeks
22kg over 53 weeks, never went past 10mg, and sulphur burps stayed mild the whole way. Posting because the loud threads are all 15mg.
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
Pen or vial? The step sizes available differ and it changes this answer.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.
- 1Weekly dosing again, half-life in the same neighbourhood as sema, so a step…11 comments in this branch · started by u/crosspost_bot_no