c/sideeffects wiki

What this community is for

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

c/sideeffects was created on 22 Aug 2023 and currently has 118,600 members and 130 captured submissions. It sits in the busiest tier of the site, which mostly affects how fast a question gets answered rather than how well.

Rules, and why each exists

Community rules come first, then the six site-wide rules that apply everywhere on GLP Research Hub. Community rules are enforced by the moderators listed at the bottom of this page; site rules are enforced by everyone.

1. Severe or escalating abdominal pain is an urgent-care question, not a forum question. We will lock those threads with a pointer to help.
2. Describe your dose, your week number and your titration speed — otherwise nobody can help.
3. No diagnosing strangers. Share what happened to you.

And the site rules, which are short on purpose:

1. Independent community. Nobody here sells anything, and anyone who tries is banned.
2. Not medical advice. Describe what you did; never prescribe to a stranger.
3. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
4. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
5. No contact handles, wallet addresses or tracking numbers — they identify people.
6. Be recognisably decent. Disagree hard, insult nobody.

Terms you will see

Vocabulary that turns up constantly in c/sideeffects. Each links to the topic page, which collects every submission that touches it.

• nausea — discussed frequently in this community — see the topic page for every submission that touches it.
• constipation — discussed frequently in this community — see the topic page for every submission that touches it.
• reflux — discussed frequently in this community — see the topic page for every submission that touches it.
• fatigue — discussed frequently in this community — see the topic page for every submission that touches it.
• hair loss — discussed frequently in this community — see the topic page for every submission that touches it.
• sulphur burps — discussed frequently in this community — see the topic page for every submission that touches it.
• gallbladder — discussed frequently in this community — see the topic page for every submission that touches it.
• heart rate — discussed frequently in this community — see the topic page for every submission that touches it.

Start here

The twelve highest-scoring submissions in this community. Not necessarily the most correct — the most agreed-with, which is a different thing, and worth remembering when you read them.

1. how much of what we believe about sulphur burps actually comes from fatigue threads — 10k points, 54 comments, 2 years ago
2. [PSA] sulphur burps are not what most of this community thinks it is — 10k points, 22 comments, 1 year ago
3. small win: fatigue stopped being a problem at week 82 — 9.7k points, 65 comments, 2 years ago
4. [Discussion] heart rate is doing more work than we give it credit for — 9.6k points, 38 comments, 2 years ago
5. [Question] how do you actually verify hair loss — 8.9k points, 31 comments, 2 years ago
6. what changed for me between month 8 and month 12 — 8.5k points, 43 comments, 2 years ago
7. someone explain nausea to me like I have not read a paper in years — 8.1k points, 42 comments, 2 years ago
8. genuine question about reflux that I am slightly embarrassed to ask — 7.9k points, 42 comments, 2 years ago
9. [PSA] gallbladder is not what most of this community thinks it is — 7.6k points, 35 comments, 1 year ago
10. help me understand heart rate, I have read the wiki twice — 7.1k points, 53 comments, 1 year ago
11. [Discussion] reflux is doing more work than we give it credit for — 7k points, 28 comments, 1 year ago
12. gallbladder — 15 things I got wrong before I got it right — 6.8k points, 67 comments, 1 year ago

Asked constantly

• [Question] resting heart rate up 7bpm, week 6, is that a thing
• muscle cramps turned out to be sodium, not magnesium
• [PSA] dizzy on standing? check whether your BP meds are now too strong
• sulphur burps: a taxonomy, a timeline, and my sincere apologies to my flatmate
• the gallbladder question that gets asked weekly, answered properly
• [Question] nausea — what am I missing here
• the reflux question that gets asked weekly, answered properly
• my hs-CRP moved and I cannot work out whether heart rate is why
• [Question] how do you actually verify gallbladder
• hair loss — my 8-week log, condensed into one table

If your question is on that list, read the answers there first. If it is not, ask it — that is what the community is for, and "this has been asked" is only a helpful reply when it comes with a link.

Who runs this

Moderation here is done by volunteers who also post as normal members. They are not clinicians, not vendors, and not paid.

• u/nausea_notes — Nausea log, 14 months, what helped and what was placebo. Ginger did nothing for me.
• u/constipation_club — Magnesium, fibre timing, hydration, movement. In that order of impact for me.
• u/quiet_moderator — I remove the obvious stuff so you never see it. Message the modmail, not me.
• u/gentle_correction — You can be right without being unkind. Usually.