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c/sideeffects·posted 3 months ago by u/sequence_checker

my hs-CRP moved and I cannot work out whether heart rate is why

Question Well Actually ×2 The Quiet One ×3

my hs-CRP moved and I cannot work out whether heart rate is why. It is the sort of thing everyone half-believes and nobody writes down.

reflux for the first eight days after each step, then nothing, every single time. Predictable enough that I started planning my week around it.

Bought four different things to fix my constipation. What actually worked was eating half as fast.

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

That is everything I have. The rest is opinion and I have tried to keep it out.

1,701 up / 247 down87% upvoted44 commentsid 1c57g48 Apr 2026

44 comments

21 in this archive, depth 5

best — the order this archive was captured in

u/baseline_drifteranalytical340 points·3 months ago

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 42 probably does not, and that is worth saying to a clinician rather than to us.

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u/constipation_clubMOD170 points·3 months ago

Left up. It is a description of one person’s week and it is flagged as such.

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u/graph_it_gary59 points·3 months ago

Left up.

Disagreeing with this one line: that symptom is not on the wait-and-see list and should not be posted as though it is.

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u/lina_dziedzic48 points·3 months ago

the food noise going quiet is the effect people came for, and sulphur burps are the toll for the first fortnight

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u/long_post_larry214 points·3 months ago

Are you eating in the couple of hours before you sleep?

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u/elin_lundgren161 points·3 months ago

Nobody warned me about muscle cramps and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

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u/zeynep_ndiaye145 points·3 months ago·edited

Not convinced by that mechanism. Slowed gastric emptying explains fullness and reflux; it does not explain what you are describing.

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u/vendorinvestigate_vic45 points·3 months ago·edited

Not convinced by that mechanism.

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/rohan_steiner70 points·3 months ago

Has anything else changed in the same window?

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u/sequence_checkerOPresearch peptides43 points·3 months ago·edited

Which day of the week relative to the shot does it hit?

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u/iman_falk74 points·3 months ago

Kept a one-line-a-day log for two months. The pattern was obvious on paper and invisible in my head.

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u/constipation_clubside effects49 points·3 months ago

if it is severe or persistent that is a clinician question, not a board question

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u/enzo_danquah17 points·3 months ago

Yes. Holding the dose is a real option and it does not mean you have failed at anything.

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u/food_noise_gonemaintenance15 points·3 months ago

Disagree. Severe abdominal pain is not on the list of things to wait out, and this board should not be treating it as one.

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u/ipamorelin_i51 points·3 months ago

On buying things to fix side effects, which I did extensively and would not do again.

The interventions that changed anything for me were all behavioural and free: smaller meals, eating slower, stopping food a few hours before sleep, more fibre and considerably more water. The things I bought did nothing I could detect, and I was motivated to detect something.

The other lever, which people forget, is time at dose. Holding rather than stepping is a legitimate plan and it fixed my tolerance where nothing else did.

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u/sequence_checkerOPresearch peptides28 points·3 months ago

Reflux was the one that got me. Stopped eating in the three hours before bed and it went from nightly to almost never.

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u/ipamorelin_i15 points·3 months ago

fatigue plus low intake is usually just low intake

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u/iman_falk16 points·3 months ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

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[removed]6 points·3 months ago

[removed by moderator]

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u/line_petrov-34 points·3 months ago

Mine settled at week 37 and has not come back since, across two more steps.

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u/mass_spec_maggieMS16 points·3 months ago

sulphur burps are unpleasant and they are not dangerous

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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