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c/sideeffects·posted 2 years ago by u/diego_sorensen

how much of what we believe about sulphur burps actually comes from fatigue threads

Discussion Well Actually ×3 Slow Clap ×1 Cold Box ×2

Slightly embarrassed to be asking this, but: how much of what we believe about sulphur burps actually comes from fatigue threads.

Nobody warned me about early fullness and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

Mine settled at week 79 and has not come back since, across two more steps.

Reflux was the one that got me. Stopped eating in the three hours before bed and it went from nightly to almost never.

Screenshot none of this. Read the whole thread, including the parts where I am told I am wrong.

10,816 up / 554 down95% upvoted54 commentsid 1kgi9f7 Oct 2023

54 comments

20 in this archive, depth 4

best — the order this archive was captured in

u/karma_irrelevant1.3k points·2 years ago

The pattern almost everyone here describes, written out once so it can be linked.

A step up is followed by a rough window — commonly sulphur burps arriving the day after the shot and easing by day four, worst in the first fortnight, then flattening out. At a stable dose it usually settles further. Constipation and fatigue tend to track intake and fluid rather than the compound directly, which is why the unglamorous answers work.

What sits outside that pattern: severe pain, symptoms that appear from nowhere weeks into a stable dose, or anything getting worse rather than better over a month. None of that is a board question and none of us can answer it for you.

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u/neha_rahimi435 points·2 years ago

constipation for the first eight days after each step, then nothing, every single time. Predictable enough that I started planning my week around it.

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u/hassan_ostergaard297 points·2 years ago

sulphur burps are unpleasant and they are not dangerous

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u/elin_trevino85 points·2 years ago

if it is severe or persistent that is a clinician question, not a board question

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[deleted]199 points·2 years ago

[deleted]

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u/quiet_moderatormod629 points·2 years ago

Bought four different things to fix my nausea. What actually worked was eating half as fast.

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u/ahmed_rasmussen762 points·2 years ago

I would be careful here. "Everyone gets this" is not true, and it makes the people who get something unusual assume they are fine when they should be asking.

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u/liv_okafor636 points·2 years ago

The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.

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u/vendorinvestigate_vic351 points·2 years ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/kavya_kravchenko420 points·2 years ago

Held the dose for an extra six weeks instead of stepping. The injection-site soreness settled and I lost the same amount anyway.

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u/tomas_lehtinen185 points·2 years ago

hair shedding follows the weight loss, not the drug, and it stops

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u/bastian_eriksen199 points·2 years ago

nobody warns you about how much of this is timing rather than dose

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u/cesar_oyelaran57 points·2 years ago

Careful with the supplement recommendation. There is no evidence for it here and the mechanism you are proposing does not hold.

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u/usp_appendixcompendial39 points·2 years ago

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

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u/ferritin_low82 points·2 years ago

Has anything else changed in the same window?

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u/quiet_moderatorMOD185 points·2 years ago

Flair set to Question. Also the standing reminder that nothing on this board is medical advice.

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u/emil_barros-9 points·2 years ago

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.

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u/neha_rahimi102 points·2 years ago

That reads like advice, and none of us can give it. Describe what you did, not what somebody else should do.

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u/gentle_correctionnice about it122 points·2 years ago

reflux at night, try not eating in the three hours before bed

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Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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