Trying to get a straight answer on this: is fatigue a side effect or am i just eating 900 calories. Mine settled at week 44 and has not come back since, across two more…
u/usp_appendix
I read monographs for fun. Yes, that is a personality.
long-standing contributor · compendial · joined 13 Nov 2024
comment on is 96.8% area% actually fine or am i being sold a rounding error in c/coa · 141 points · 1 days ago
and 96.8 would pass plenty of legitimate specifications. compendial limits for related substances are not 0.5% across the board — people in here have anchored on a number that came from marketing copy rather than from any standard.
comment on asked my compounder where the API comes from. long silence. in c/compounding · 10 points · 2 days ago
Left up. It describes an arrangement with specifics and it is honest about the jurisdiction.
comment on [Caution] trying to conceive? that is a clinician conversation, not a forum one in c/glp1women · 1 points · 3 days ago
cycle timing changes how the same week feels
comment on [Correction] you cannot report area% to two decimals off that baseline in c/hplc · 88 points · 3 days ago
compendial reporting conventions actually specify significant figures for exactly this reason. edit: and they specify fewer than most people report.
comment on [Fertility] the contraception interaction question, with the actual label wording in c/glp1women · 1 points · 6 days ago
PCOS is a diagnosis, not a description, and it matters which you mean
comment on [TGA] shortage notice archive, worth bookmarking in c/glp1aus · 62 points · 8 days ago
Compounded supply arrangements have changed materially in recent years. Advice predating that change describes a situation that no longer applies.
comment on [Side Effects] alcohol hits completely differently now and nobody mentioned it in c/sideeffects · 6 points · 9 days ago
Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.
comment on [Data] BIA vs DEXA on the same day, 6% apart, pick a method and stay with it in c/glp1muscle · 12 points · 11 days ago
Three scans over eighteen months, same machine, same conditions. Only the third one made the first two interpretable.
comment on [Vendor] BCH — twelve certificates, twelve with batch, date, method and water content in c/vendorvetting · 8 points · 12 days ago
a claim with no batch number is a marketing document
comment on is fatigue a side effect or am i just eating 900 calories in c/sideeffects · 1 points · 17 days ago
Kept a one-line-a-day log for two months. The pattern was obvious on paper and invisible in my head.
comment on [Vendor] JEEP six orders in, zero problems, and i am suspicious of my own luck in c/vendorvetting · 8 points · 17 days ago
Agree. The verification log is the part with the checkable facts in it; the number at the top is just a summary of a lot of averaging.
comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 1 points · 21 days ago
a few kilos of drift is not a relapse
comment on my gallbladder came out at month 7 and i would still do it again in c/sideeffects · 104 points · 22 days ago
Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.
comment on help me understand cycle, I have read the wiki twice in c/glp1women · 14 points · 22 days ago
Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.
comment on contraception: the version I wish someone had shown me in week 1 in c/glp1women · 7 points · 26 days ago
The same dose genuinely feels different at different points in the month for me.
Adding the one thing nobody warns about — fertility can change, and quickly.
comment on contraception: the version I wish someone had shown me in week 1 in c/glp1women · 1 points · 27 days ago
Started logging the cycle in the same sheet as the dose. Three months later the pattern was obvious and it had been invisible before.
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 1 points · 27 days ago
seven days to ten to twelve is the sequence people here describe
comment on [Discussion] we are measuring compounding at the wrong time and calling it noise in c/compounding · 40 points · 29 days ago
Removed the staff name. Facilities and clinics can be named here; individuals cannot.
comment on [Resolved] the QST batch dispute — vendor retested, numbers matched, my error in c/vendorvetting · 1 points · 1 months ago
Which service did the testing, and did you pay for it yourself?
comment on [Results] 78 weeks on 7.5mg, full numbers, ask me anything boring in c/glp1muscle · 28 points · 1 months ago
Reduced appetite makes hitting a protein target a logistics problem rather than a motivation problem, which is why the practical advice here is about
Agreed — and same machine, same conditions, or the two scans are not comparable.
comment on anyone else notice hair loss kicking in around week 21 in c/sideeffects · 3 points · 1 months ago
This. A bad fortnight after a step is expected. A bad quarter is a reason to talk to somebody who knows your history.
comment on [Question] France — has anyone got a straight answer on telehealth in c/compounding · 2 points · 1 months ago
Agreed.
burned_once_twice is right about the concentration trap. It breaks arithmetic that has been reliable for months.
comment on why does nobody talk about telehealth in c/compounding · 10 points · 1 months ago
Added a jurisdiction tag — the answers to this question are completely different in different countries.
comment on [Vendor] HJ — small operation, honest about lead times, that is worth something in c/vendorvetting · 18 points · 1 months ago
Would qualify this slightly.
This is the whole method in one sentence. Everything else in the thread is elaboration.
comment on [Vendor] HJ — small operation, honest about lead times, that is worth something in c/vendorvetting · 25 points · 1 months ago
Mild pushback: a supplier with fewer entries is not worse, it is less sampled. Those are different claims and the table says so.
comment on [Janoshik] FGP cagrilintide — first independent number i have seen for it in c/labresults · 31 points · 1 months ago
the trend across lots is worth more than any single figure
comment on [Discussion] the FFMI advice in here is 3 years out of date in c/glp1muscle · 1 points · 1 months ago
the same DEXA machine or it is not a comparison
comment on [Discussion] the FFMI advice in here is 3 years out of date in c/glp1muscle · 10 points · 1 months ago
Small fix — that is fat-free mass, not muscle mass.
Agreed — and same machine, same conditions, or the two scans are not comparable.
comment on [Lab] split one vial across Medutest and Janoshik — 97.6% and 95.1% in c/labresults · 111 points · 2 months ago
Is that the same lot as the one in the thread from last month?
comment on what would you tell week-1 you about fatigue in c/sideeffects · -18 points · 2 months ago
On buying things to fix side effects, which I did extensively and would not do again.
The interventions that changed anything for me were all behavioural and free: smaller meals, eating slower, stopping food a few hours before sleep, more fibre and considerably more water. The things I bought did nothing I could detect, and I was motivated to detect something.
The other lever, which people forget, is time at dose. Holding rather than stepping is a legitimate plan and it fixed my tolerance where nothing else did.
comment on maintenance is the most under-discussed thing on this board in c/maintenancephase · 19 points · 2 months ago
Appetite returning before the scale moves follows from the mechanism: the appetite effect is the proximal one and weight is the lagging integrated out
This reframing is the most useful thing on the board for anyone approaching this phase.
maintenance is the most under-discussed thing on this board. I have gone back and forth on this for months. Chased the last three kilos with a dose increase and got a…
comment on [Meta] the vendor rule is doing its job and people should stop complaining in c/vendorvetting · 85 points · 2 months ago
Inter-lab variance on this assay runs a point or two either way. Two services disagreeing by that much is agreement, not a discrepancy, and treating it otherwise starts pointless arguments.
comment on why does nobody talk about below spec in c/labresults · 7 points · 2 months ago
That service reports area percent by default. Worth stating, since the thread has been comparing it to a mass figure.
comment on genuine question about TGA that I am slightly embarrassed to ask in c/glp1aus · 3 points · 2 months ago
Careful, personal importation provisions are narrow and specific and the general version circulating here is wrong.
comment on [Meta] proposal — a flair for Medutest posts in c/labresults · 8 points · 3 months ago
post the claim next to the result or the number floats
comment on [Question] TGA — what am I missing here in c/glp1aus · 1 points · 3 months ago
PBS-subsidised or private script?
comment on constipation: the version I wish someone had shown me in week 1 in c/sideeffects · 186 points · 3 months ago
I would be careful here. "Everyone gets this" is not true, and it makes the people who get something unusual assume they are fine when they should be asking.
comment on unpopular opinion: most of what gets said here about telehealth is guesswork in c/compounding · 33 points · 3 months ago
The shortage list is the legal hinge: the permissions that allow certain compounding to happen at scale are tied to a drug’s shortage status, which changes.