maintenance is the most under-discussed thing on this board
maintenance is the most under-discussed thing on this board. I have gone back and forth on this for months.
Chased the last three kilos with a dose increase and got a fortnight of nausea and no change in the number.
Been at maintenance for 23 months on 0.5mg. Nothing happens. That is the whole report and it took me a while to accept it as success.
Weigh monthly now. Best change I made in the whole run and it cost nothing.
Ask me anything specific. Anything general I will probably get wrong.
best — the order this archive was captured in
Interval stretching changes the exposure profile: with a week-long half-life, moving to ten or twelve days lowers trough concentration more than it lowers average exposure. That is why appetite return is often the first thing noticed.
What is the plan if the drift continues for another month?
Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.
I would not treat a two-kilo range as drift requiring action. That is ordinary weight variation.
Two years at maintenance. The logistics are the only remaining work — ordering, storing, remembering.
the trials that looked at withdrawal are unambiguous about what follows
Not convinced. Interval stretching changes your exposure profile, not just the total, and the two are not equivalent.
Drifted up 9kg over a winter and panicked. It came back off without any change, which is apparently just what weight does.
find the dose that holds, then stop optimising
Left up. It is a maintenance report with a duration attached and those are rarer than they should be.
Body weight varies by a couple of kilos over days in stable people through fluid, glycogen and gut content. A range is not a trend.
Maintenance is the phase with the least published guidance and the most individual variation, which is precisely why board consensus here is worth less than usual.
Maintenance is the phase with the least published guidance and the most individual variation, which is precisely why board consensus here is worth les
Adding one thing — decide what maintenance looks like before you arrive at it.
That reads like a taper schedule and this board cannot hand those out.
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Same. Monthly is plenty at this stage and daily weighing made me miserable for no information gain.
monthly weigh-ins are enough at this stage
Appetite returning before the scale moves follows from the mechanism: the appetite effect is the proximal one and weight is the lagging integrated outcome.
Appetite returning before the scale moves follows from the mechanism: the appetite effect is the proximal one and weight is the lagging integrated out
This reframing is the most useful thing on the board for anyone approaching this phase.
Careful — a dose reduction plan is a conversation with someone who knows your history, not a board consensus.
Correction: that trial measured regain after withdrawal, not failure of the drug during treatment. Very different claim.
do not chase the last two kilos with a dose increase
- 1Interval stretching changes the exposure profile: with a week-long…6 comments in this branch · started by u/gradient_goblin