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c/sideeffects·posted 13 days ago by u/adaeze_batista

muscle cramps turned out to be sodium, not magnesium

Question Clean Column ×7

muscle cramps turned out to be sodium, not magnesium. Change my mind, genuinely — I have no stake in being right about this.

The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.

Nobody warned me about fatigue and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

Kept a one-line-a-day log for two months. The pattern was obvious on paper and invisible in my head.

Ask me anything specific. Anything general I will probably get wrong.

4,762 up / 4,237 down53% upvoted24 commentsid dqt8q017 Jul 2026

24 comments

24 in this archive, depth 4

best — the order this archive was captured in

u/step_therapy_s96 points·12 days ago

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.

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u/long_post_larry80 points·11 days ago

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal.

Agreed, with the caveat that "usually settles" is not "always settles" and the exceptions should still get asked about properly.

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u/adaeze_batista-28 points·11 days ago

How long after a step up did this start?

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u/adaeze_batistaOP1 point·11 days ago

Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.

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u/elin_lindqvist28 points·11 days ago

Cosigning the fibre and water answer. Unglamorous, free, and it fixed it for me inside a week.

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u/brigade_detector47 points·11 days ago·edited

Are you eating in the couple of hours before you sleep?

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[deleted]17 points·11 days ago

[deleted]

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u/idris_iyer10 points·11 days ago

Is it every week or did it start at a particular dose?

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u/cesar_oyelaran55 points·12 days ago

hair shedding follows the weight loss, not the drug, and it stops

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u/iman_falk21 points·12 days ago

fatigue plus low intake is usually just low intake

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u/zeynep_zielinski7 points·12 days ago

Same pattern here. It settled at a stable dose without me doing anything clever.

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u/sofia_wikstrom40 points·12 days ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/rina_bergstrom16 points·12 days ago·edited

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

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u/hassan_castellanos32 points·12 days ago

Correction: that is a known effect of reduced intake rather than a direct drug effect. The distinction matters because the fix is different.

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u/vendorinvestigate_vic36 points·12 days ago

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

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u/slow_logbook_ftw23 points·11 days ago·edited

That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.

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u/enzo_danquah14 points·11 days ago·edited

That symptom is not the one being described upthread.

slow_logbook_ftw is right about the timing. The day-of-week pattern is the diagnostic bit, not the severity.

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u/insulin_syringe_ian18 points·10 days ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/zaid_balogun9 points·10 days ago

Pushback: you changed the dose, the meal timing and the training in the same fortnight, so the attribution is guesswork.

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u/ilias_cabrera6 points·10 days ago

nobody warns you about how much of this is timing rather than dose

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u/milan_villalobos3 points·10 days ago

Yes — the day-two-to-day-four window is so consistent across this board that it is almost diagnostic.

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u/mikkel_kimani13 points·11 days ago

Held the dose for an extra six weeks instead of stepping. The muscle cramps settled and I lost the same amount anyway.

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u/adaeze_batistaOP8 points·11 days ago

Correcting my own comment above: I said day three and my log says day two. Same pattern, wrong day.

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u/piotr_bruun5 points·11 days ago

Correcting my own comment above: I said day three and my log says day two.

This is the shape almost everybody here describes, and it is the single most reassuring thing in the thread.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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