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c/semaglutide·submitted 1 months ago by u/sorted_by_new

[Side Effects] the sulphur burps are real and they do pass

Side Effectsbranch of 9 comments

Something I keep coming back to: the sulphur burps are real and they do pass. reflux made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it. What I would tell week-one me, in order of how much time it would have saved. One: the first month is a…

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9 comments, started 1 months ago
u/vikram_ferreira140 points·1 months ago

Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.

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u/elodie_grimaldi114 points·1 months ago

Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chem

vikram_ferreira is describing the standard shape here and it matches the trial data better than most anecdotes do.

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u/hugo_bergstrom43 points·1 months ago

This matches me almost exactly, right down to the sulphur burps showing up on the second day and being gone by the fourth.

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u/sorted_by_newOP25 points·1 months ago

This matches me almost exactly, right down to the sulphur burps showing up on the second day and being gone by the fourth.

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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u/prior_auth_painappeals7 points·1 months ago

if 1.0mg is working there is no prize for going up

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u/zofia_lindholm-17 points·1 months ago

sema is weekly for a reason, the half-life does the smoothing

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u/sorted_by_newOP28 points·1 months ago

the appetite signal and the scale move on different clocks

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u/titration_marshalmod · c/semaglutide43 points·1 months ago

the ladder exists because the gut needs the time, not because the pharmacy likes paperwork

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u/sorted_by_newOP24 points·1 months ago

What dose and how many weeks at it before this started?

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