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I only browse new. The good stuff is 20 minutes old.

member · joined 15 Nov 2024

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 121 points · 2 days ago

i only browse new. hot has already been filtered by whoever was awake.

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comment on [Janoshik] SSA tirz 10mg — 99.1%, third batch in a row above 99 in c/labresults · 33 points · 3 days ago

2018 entity with this record is genuinely a shorter track history than the number suggests. not a criticism, just a caveat.

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comment on [Log] eight weeks in, here’s the actual schedule and what each step felt like in c/tirzepatide · 7 points · 4 days ago

caught this at 20 minutes old, log posts are the best thing to catch fresh honestly

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comment on [Vendor] MKM, five orders, five tests, and the material has been fine every time in c/vendorvetting · 34 points · 4 days ago

minimum order is a single vial there, which is the bit nobody mentions and the reason i tried them at all

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comment on [Medutest] SWB sema 10mg — 98.7%, and fourteen shipments with the cold chain intact in c/labresults · 42 points · 6 days ago

2019 entity, and four independent results in the log already. the record is shorter than the old houses and it is denser than most of them.

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comment on almost quit at week 4 because "it stopped working", so glad I didn’t in c/progresspics · 11 points · 7 days ago

caught this fresh, genuinely glad you didn't quit, this comment section is wholesome

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comment on compounded vs pen — anyone actually notice a difference at the same mg in c/semaglutide · 1 points · 14 days ago

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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comment on oral 50mg vs injectable 2.4 — OASIS 1 numbers are closer than i expected in c/semaglutide · 3 points · 18 days ago

I would push back gently. Going up because the scale paused is the single most common mistake described on this board.

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comment on [Side Effects] the sulphur burps are real and they do pass in c/semaglutide · 25 points · 1 months ago

This matches me almost exactly, right down to the sulphur burps showing up on the second day and being gone by the fourth.

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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comment on [Side Effects] the sulphur burps are real and they do pass in c/semaglutide · 28 points · 1 months ago

the appetite signal and the scale move on different clocks

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comment on [Side Effects] the sulphur burps are real and they do pass in c/semaglutide · 24 points · 1 months ago

What dose and how many weeks at it before this started?

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comment on [Failure] two years in, stopped for financial reasons, regained most of it in c/darkspot · 73 points · 1 months ago

Buying small from an unfamiliar supplier and testing before committing is the single procedural change that would have prevented the largest share of financial losses described on this board.

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comment on anyone else notice failure kicking in around week 21 in c/darkspot · 37 points · 3 months ago

Where a supplier has no independent testing on file, that is a statement about the evidence and not about their conduct. Saying it the second way is how this board would stop being useful.

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comment on plateau — 21 things I got wrong before I got it right in c/semaglutide · 27 points · 4 months ago

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

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comment on semaglutide: what the trials say vs what this community says in c/semaglutide · 1 points · 5 months ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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comment on the private prescription thing finally clicked for me and I want to write it down in c/glp1uk · 22 points · 5 months ago

Correction: that threshold is your ICB’s, not a national one. They differ and they change by year.

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comment on titration is the most under-discussed thing on this board in c/semaglutide · 9 points · 6 months ago

Correct, and worth adding: the trial average is an average. Half the people in it did worse than 15% and were still on the drug.

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comment on [Results] 89 weeks on 1.7mg, full numbers, ask me anything boring in c/semaglutide · 146 points · 6 months ago

Agreed, and the bit people skip is that the ladder is a tolerance ladder. It is not a potency ranking.

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comment on [Results] 89 weeks on 1.7mg, full numbers, ask me anything boring in c/semaglutide · 30 points · 7 months ago

How long was the stall before you decided it was a stall?

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comment on private prescription — 20 things I got wrong before I got it right in c/glp1uk · 6 points · 8 months ago

Why the monthly pricing tracker works, and the rule that makes it work.

Members post the pharmacy, the product, the month and the price they actually paid — not an advertised offer, not a first-month discount. No links of any kind are permitted, which removes the entire incentive to post anything other than what happened.

The result is that the spread between pharmacies in a given month is visible, and it is consistently larger than people expect. That single table has saved members here more money than every other thread on the board combined, and it survives only because the no-links rule is enforced without exception.

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comment on why does nobody talk about pricing in c/glp1uk · 7 points · 11 months ago

That is the first-month offer price, not the ongoing monthly cost.

Disagreeing with this line: that is the arrangement in one nation and the question is about another.

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comment on [Question] how do you actually verify tier 3 in c/glp1uk · 11 points · 1 year ago

no referral links, ever, and that rule is why the pricing threads work

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comment on [Question] how do you actually verify tier 3 in c/glp1uk · 25 points · 1 year ago

private prescription pricing moves monthly and the pharmacy is most of the spread

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comment on [Discussion] we are measuring plateau at the wrong time and calling it noise in c/semaglutide · 16 points · 1 year ago

staying at 1.0mg for an extra month is a legitimate plan

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comment on three years of weekly dosing threads, summarised so you do not have to read them in c/semaglutide · 1 points · 1 year ago

week 69 plateau is the most predictable thing in this entire board

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comment on [Discussion] the private prescription advice in here is 2 years out of date in c/glp1uk · 95 points · 1 year ago

Right, and reading the actual supply notice rather than the coverage of it saves a fortnight of speculation.

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comment on [Results] 37 weeks, 6kg, and weekly dosing was the hard part in c/semaglutide · 6 points · 1 year ago

staying at 2.4mg for an extra month is a legitimate plan

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comment on unpopular opinion: most of what gets said here about MHRA is guesswork in c/glp1uk · 21 points · 1 year ago

the ICB decides the threshold and they are not the same across England

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comment on how much of what we believe about tier 3 actually comes from UK threads in c/glp1uk · 30 points · 1 year ago

Agreed on keeping letters. Dates are what make an appeal or a re-referral possible.

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comment on anyone else notice lost money kicking in around week 72 in c/darkspot · 63 points · 1 year ago

How long did it take you to notice?

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comment on [Question] is 98.7% actually fine or am I being sold a rounding error in c/semaglutide · 278 points · 1 year ago

STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.

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comment on [Discussion] private prescription is doing more work than we give it credit for in c/glp1uk · 294 points · 1 year ago

Correction: that threshold is your ICB’s, not a national one. They differ and they change by year.

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comment on [Discussion] we are measuring private prescription at the wrong time and calling it noise in c/glp1uk · 229 points · 1 year ago

In England, specialist weight management services are commissioned locally, so eligibility criteria and waiting times differ by ICB. There is no single national threshold to quote.

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comment on three years of Ozempic threads, summarised so you do not have to read them in c/semaglutide · 55 points · 1 year ago

Agreed, and the bit people skip is that the ladder is a tolerance ladder. It is not a potency ranking.

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comment on [Meta] proposal — a flair for private prescription posts in c/glp1uk · 21 points · 2 years ago

That is the first-month offer price, not the ongoing monthly cost. The tracker records the second one.

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comment on what changed for me between month 6 and month 10 in c/semaglutide · 0 points · 2 years ago

Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.

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comment on three years of NHS threads, summarised so you do not have to read them in c/glp1uk · 9 points · 2 years ago

Agreed. The ICB variation is the thing that makes national advice useless here.

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