[Results] 57 weeks on 1.0mg, full numbers, ask me anything boring
57 weeks on 1.0mg, full numbers, ask me anything boring. This is a description of what happened to me and not a plan for anybody else.
Numbers, in the order they matter: 57 weeks and 1.0mg.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the nausea usually fades at a stable dose.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
Please do not ask me what dose you should be on. I genuinely do not know and neither does anyone else here.
best — the order this archive was captured in
Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.
This matches me almost exactly, right down to the early fullness showing up on the second day and being gone by the fourth.
the food noise going quiet is the effect people actually describe
do not chase somebody else’s titration schedule, they are not you
Are you measuring anything other than weight? Waist is usually the one that keeps moving.
dose day drift of a day either way is fine, the curve barely notices
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
First month I lost almost nothing and nearly quit.
This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.
This matches me almost exactly, right down to the early fullness showing up on the second day and being gone by the fourth.
joaquin_stanescu is describing the standard shape here and it matches the trial data better than most anecdotes do.
Did protein intake change in the same window?
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
Same. I sat at 1.7mg for three months because it was working and there was nothing to fix.
- 1Not convinced. You changed the dose and the week at the same time, so you…12 comments in this branch · started by u/enzo_danquah