[Vendor] WWB vs QST on the same compound, same month — both cleared 98.5%
WWB vs QST on the same compound, same month — both cleared 98.5%. I will put the method line and the batch identifier up front because that is what makes this checkable.
The relevant figures are 98.5%, and they come from the same log I have kept the whole time.
Dropped my injection day by two days once because of travel. Nothing happened. The panic was worse than the effect.
Kept a log from week one and the single most useful column turned out to be waist, not weight.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
- WWWWB source pageWuhan Wansheng Biotechnology Co., Ltd. · Wuhan · 97% here, rank 2 · shop at wuhanwanshengbio.com →
- QSQST source pageQingdao Saber Technology Pharmaceutical · Qingdao · 94% here, rank 9 · shop at qingdaosabertechnology.com →
nofollow and sponsored; nobody here is paid for it.best — the order this archive was captured in
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
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Are you measuring anything other than weight? Waist is usually the one that keeps moving.
Genuine question — is the appetite effect still there, or is it just the scale that has paused?
Strongly agree on protein. It did more for my nausea than any of the things I bought to fix my nausea.
Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
Disagree with this specific line. A pause at 1.7mg is not evidence that 1.7mg has stopped working.
Disagree with this specific line.
Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.
Sat at 0.5mg for four months because it was doing the job. Everyone told me to go up. The one time I did, the only thing that changed was the early fullness.
What dose and how many weeks at it before this started?
What dose and how many weeks at it before this started?
This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the constipation usually fades at a stable dose.
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.
week 59 plateau is the most predictable thing in this entire board
week 59 plateau is the most predictable thing in this entire board
hassan_castellanos is describing the standard shape here and it matches the trial data better than most anecdotes do.
the first four weeks are a tolerance check, not a weight-loss phase
Leaving this up. It is a check-in, it has numbers, and it is honest about being one person.
do not chase somebody else’s titration schedule, they are not you
Minor fix — the half-life is about a week, not about a day. The rest of your point stands.
dose day drift of a day either way is fine, the curve barely notices
Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.
That figure is the 68-week trial mean, not a weekly rate.
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
- 1The escalation schedule in the trials existed to keep people on the drug. It…11 comments in this branch · started by u/leila_vasquez
- 2the first four weeks are a tolerance check, not a weight-loss phase11 comments in this branch · started by u/camila_mensa