[Meta] proposal — a flair for SURMOUNT posts
proposal — a flair for SURMOUNT posts. Nothing about this affects the ranking maths, before anyone asks.
Switching from semaglutide, since three people asked in this thread alone.
There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.
None of that is a recommendation. It is what the threads say, and the threads are not a clinic.
Week 37 was the first time the scale moved after a five-week stall. I changed nothing in that window.
The thing nobody warned me about was how much of this is logistics — storing it, remembering it, the same day every week.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
best — the order this archive was captured in
The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.
28kg over 59 weeks, never went past 10mg, and sulphur burps stayed mild the whole way. Posting because the loud threads are all 15mg.
The four-week interval in the label is a minimum. Nothing about the pharmacology requires you to step on schedule, and the trials stepped on a calendar because trials have to.
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
28kg over 59 weeks, never went past 10mg, and sulphur burps stayed mild the whole way.
This. The step interval is a floor, and reading it as a timetable is the most expensive mistake in the thread.
SURMOUNT-1 landed around 21% at 72 weeks on the top arm
SURMOUNT-1 landed around 21% at 72 weeks on the top arm
teodor_szabo is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.
teodor_szabo is right that the two molecules are not interchangeable.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
Appetite effect for me is flat across seven days.
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.
- 128kg over 59 weeks, never went past 10mg, and sulphur burps stayed mild the…9 comments in this branch · started by u/vito_chowdhury