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c/sideeffects·posted 8 months ago by u/ilias_cabrera

[Question] how do you actually verify heart rate

Question Slow Clap ×4

Genuine question, and the title is the question: how do you actually verify heart rate.

Nobody warned me about constipation and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.

544 up / 163 down77% upvoted27 commentsid fyt7rr11 Nov 2025

27 comments

18 in this archive, depth 5

best — the order this archive was captured in

u/zaid_balogun-6 points·8 months ago

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 20 probably does not, and that is worth saying to a clinician rather than to us.

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u/tomas_broberg1 point·8 months ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/ayesha_radich1 point·8 months ago

Mine settled at week 42 and has not come back since, across two more steps.

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u/janoshik_junkieindependent tester1 point·8 months ago

Yes — the day-two-to-day-four window is so consistent across this board that it is almost diagnostic.

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u/halima_mbeki1 point·8 months ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/naomi_erdogan0 points·8 months ago

Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.

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u/ilias_cabreraOP1 point·8 months ago·edited

a rough fortnight at each step is normal, a rough three months is not

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u/brigade_detector1 point·8 months ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/adaeze_batista46 points·8 months ago

reflux at night, try not eating in the three hours before bed

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u/tomas_lehtinen13 points·8 months ago

This. A bad fortnight after a step is expected. A bad quarter is a reason to talk to somebody who knows your history.

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u/elin_lundgren6 points·8 months ago

Same pattern here. It settled at a stable dose without me doing anything clever.

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u/chidi_abubakar11 points·8 months ago

fatigue plus low intake is usually just low intake

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u/iman_castellanos4 points·8 months ago

Which day of the week relative to the shot does it hit?

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u/ferran_dahlberg1 point·8 months ago

sulphur burps are unpleasant and they are not dangerous

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u/hassan_castellanos1 point·8 months ago

Reflux was the one that got me. Stopped eating in the three hours before bed and it went from nightly to almost never.

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u/tomas_broberg1 point·8 months ago

sulphur burps are unpleasant and they are not dangerous

ferran_dahlberg is right about the timing. The day-of-week pattern is the diagnostic bit, not the severity.

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u/chidi_demir3 points·8 months ago

the reflux that arrives at week 73 out of nowhere is usually something else

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u/elin_lindqvist20 points·8 months ago

the first fortnight after a step is the worst of it, then it settles

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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