[Discussion] can we stop arguing about plateau until somebody posts a number
can we stop arguing about plateau until somebody posts a number. I am not trying to be the "source?" guy. I would just like a source.
My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.
The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.
best — the order this archive was captured in
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
What I would tell week-one me, in order of how much time it would have saved.
One: the first month is a tolerance check. You are finding out whether you can take this, not how much you will lose. Two: write down the dose, the day and the waist measurement. Three: a stall of under six weeks is weather, not climate. Four: reflux that arrives the day after the shot and fades by day four is the ordinary pattern and it usually settles at a stable dose.
None of that is advice about what you should do. It is the shape of the thing, which nobody explained to me and which the wiki explains better than I just did.
Same. I sat at 0.5mg for three months because it was working and there was nothing to fix.
Correct, and worth adding: the trial average is an average. Half the people in it did worse than 15% and were still on the drug.
Same injection day each week, or has it drifted?
protein first, then everything else gets easier
Retitled to match the body. The original promised a comparison the post does not make.
if 0.5mg is working there is no prize for going up
What did week 87 look like compared with this one? The month either side is the useful comparison.
The mental model that finally made this click for me: there are two curves, and people watch the wrong one.
The first is exposure, which is set by the dose and smoothed by a week-long half-life. It changes when you change the dose and then settles over about a month. The second is body weight, which is exposure filtered through appetite, food, water, sleep, training and the scale itself, and which moves in steps rather than a line.
Almost every "it stopped working" post is somebody watching curve two over a fortnight and drawing conclusions about curve one. If the appetite effect is still there, exposure is fine. Wait the month.
Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.
sema is weekly for a reason, the half-life does the smoothing
- 1Retitled to match the body. The original promised a comparison the post does…6 comments in this branch · started by u/titration_marshal