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c/glp1muscle·posted 11 months ago by u/zaid_roos

[Discussion] we are measuring lean mass at the wrong time and calling it noise

Discussion Long Haul ×8 Sourced ×1

we are measuring lean mass at the wrong time and calling it noise. Change my mind, genuinely — I have no stake in being right about this.

Reduced appetite makes hitting a protein target a logistics problem rather than a motivation problem, which is why the practical advice here is about timing and food choice rather than willpower.

Hydration status and fasting state affect the lean mass estimate. Standardising both is the difference between a comparison and a coin toss.

Fat-free mass index is a ratio of fat-free mass to height squared. It moves when either term does, which makes it awkward to interpret during active weight change.

That is everything I have. The rest is opinion and I have tried to keep it out.

1,698 up / 94 down95% upvoted53 commentsid 4az0lw8 Aug 2025

53 comments

24 in this archive, depth 5

best — the order this archive was captured in

u/long_post_larry-16 points·11 months ago

On comparing yourself to composition figures from trials.

Published composition data comes from supervised populations with structured protocols, standardised scanning, and analysis populations that have been defined in advance. Your two scans at a local clinic, taken in different states of hydration, are not the same measurement.

Use your own baseline. The question worth asking is whether your own trajectory is going the way you want given what you are actually doing, and the honest answer usually requires measuring protein rather than estimating it and being truthful about training frequency. Neither of those is advice — a programme and a target are things to work out with somebody who knows your history.

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u/lift_heavy_thingsMOD1 point·11 months ago·edited

Reminder that nobody here is prescribing training and the sidebar says so.

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u/saskia_wojcik222 points·11 months ago

Yes. Nobody here is prescribing training or nutrition and the good posts say so.

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u/zaid_roosOP124 points·11 months ago

Same DEXA machine both times?

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u/zaid_roosOP70 points·11 months ago

Correcting myself upthread: 23 months between scans, not the figure I gave.

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u/draw_up_dizzy53 points·11 months ago

Yes. Lean mass change during weight loss is expected; the useful question is the proportion, not whether it happens.

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[removed]35 points·11 months ago

[removed by moderator]

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u/edit_for_clarity69 points·11 months ago

strength retention is a decent proxy and it is free

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u/ferran_krastev100 points·11 months ago

Protein was the whole problem. Appetite dropped and I was eating well under target without noticing for a month.

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u/meera_oyelaran132 points·11 months ago

Strength retention is an imperfect but free longitudinal proxy: it is affected by neural factors and by being in a deficit, so it tracks tissue change loosely rather than exactly.

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u/zaid_roosOP97 points·11 months ago

the appetite effect makes eating enough protein a logistics problem

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u/throwaway_titration130 points·11 months ago

Two scans on the same machine 15 months apart. Lean mass held better than I expected and the lifts told the same story for free.

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u/trialwatch_theotrial nerd60 points·11 months ago·edited

Two scans on the same machine 15 months apart.

This is the whole intervention. Protein and resistance training.

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u/cold_chromatogram38 points·11 months ago·edited

This is the whole intervention.

Disagreeing with this line: rate alone does not preserve lean mass. The training does.

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u/alcohol_aversion12 points·11 months ago

resistance training first, cardio if there is time left

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u/lina_dziedzic5 points·11 months ago

nothing on this board is a training or nutrition prescription

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u/dario_stanescu85 points·11 months ago

Some lean mass loss accompanies weight loss in any deficit. Resistance training and adequate protein intake are the two interventions with the best evidence for limiting the proportion.

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u/halima_mbeki81 points·11 months ago

Three scans over eighteen months, same machine, same conditions. Only the third one made the first two interpretable.

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u/first_pen_fear65 points·11 months ago

lean mass loss during weight loss is expected, the question is how much

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u/throwaway_wl202639 points·11 months ago

lean mass loss during weight loss is expected, the question is how much

first_pen_fear is right that protein becomes a logistics problem when appetite drops.

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u/viktor_girard17 points·11 months ago

first_pen_fear is right that protein becomes a logistics problem when appetite drops.

Adding the free proxy — track a few lifts monthly. It costs nothing and it is longitudinal.

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u/maintenance_mode_maxmaintenance37 points·11 months ago

Correction: those scans are from different machines, and the difference you are describing is within the measurement error.

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u/amylin_amyamylin67 points·11 months ago·edited

Started weighing protein rather than estimating it. The gap between what I thought and what I ate was embarrassing.

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Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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