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u/chidi_demir

Contributes reviews on supplier material. Based in Split.

member · joined 12 Mar 2025

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Overview — page 3 of 3

comment on [Meta] proposal — a flair for 503A posts in c/compounding · 50 points · 1 year ago

This. Compounded preparations carry no equivalence claim, and treating them as generics is a category error people make constantly.

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comment on [Meta] the Wegovy rule is doing its job and people should stop complaining in c/semaglutide · 5 points · 1 year ago

Correcting myself from earlier in the thread: I said week 4 and it was week 13. Same shape, wrong number.

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comment on [Meta] the Wegovy rule is doing its job and people should stop complaining in c/semaglutide · 8 points · 1 year ago

What dose and how many weeks at it before this started?

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comment on [Discussion] purity is doing more work than we give it credit for in c/coa · 29 points · 1 year ago

Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.

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comment on [Discussion] carrier is doing more work than we give it credit for in c/intlshipping · 251 points · 1 year ago

A lane is an origin, a destination, a carrier and a season. Change any one and the distribution changes, which is why supplier-level shipping averages are close to meaningless.

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comment on the prescription thing finally clicked for me and I want to write it down in c/glp1eu · 19 points · 1 year ago

That shortage notice was national and does not apply where the question is coming from.

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comment on [Vendor] JEEP vs WXT on the same compound, same month — both cleared 98.5% in c/coa · 1 points · 1 year ago

The PDF creation date being later than the analysis date is usually a re-issue or a re-export.

This is the sentence to take away. The rest of the thread is footnotes to it.

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comment on three years of 2.4mg threads, summarised so you do not have to read them in c/semaglutide · 354 points · 1 year ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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comment on 21 months in and semaglutide is still the thing I get wrong in c/semaglutide · 52 points · 1 year ago

Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.

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comment on what would you tell week-1 you about gallbladder in c/sideeffects · 69 points · 1 year ago

That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.

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comment on three years of water content threads, summarised so you do not have to read them in c/coa · 209 points · 1 year ago

Spent four months confusing area% and mass% in every post I made here. One explainer thread and it clicked permanently.

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comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 0 points · 1 year ago

Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.

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comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 78 points · 1 year ago

Do sulphur burps track the day after the shot, or is it there all week?

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comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 43 points · 1 year ago

the first four weeks are a tolerance check, not a weight-loss phase

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comment on help me understand area percent, I have read the wiki twice in c/coa · 193 points · 1 year ago

Ask what the stability statement was written against — temperature, light, and whether it was the lyophilised powder or the reconstituted solution. Those are three different claims.

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comment on three years of Apotheke threads, summarised so you do not have to read them in c/glp1eu · 33 points · 1 year ago

Agreed — authorisation is European, reimbursement is national, and almost every confused thread here misses that split.

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comment on help me understand lane, I have read the wiki twice in c/intlshipping · 35 points · 1 year ago

That is a packaging observation, not a transit observation. Worth posting, worth separating.

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comment on DHL — 21 things I got wrong before I got it right in c/intlshipping · 12 points · 2 years ago

What lead time were you quoted at checkout?

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comment on someone explain survodutide to me like I have not read a paper in years in c/survodutide · 14 points · 2 years ago

Read the phase 2 hepatic paper properly and the endpoint definitions were more interesting than the headline response rate.

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comment on Apotheke — 10 things I got wrong before I got it right in c/glp1eu · 11 points · 2 years ago

That is an authorisation question and you have answered a reimbursement one. They are decided by different bodies.

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comment on transit time — 12 things I got wrong before I got it right in c/intlshipping · 14 points · 2 years ago

A quoted lead time is a commitment you can evaluate. Measuring quoted against actual across several orders tells you more about an operation than the raw speed does.

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comment on transit time — 12 things I got wrong before I got it right in c/intlshipping · 55 points · 2 years ago

Push back: comparing a July transit with a February one on the same lane is not a comparison.

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comment on why does nobody talk about biopsy in c/survodutide · 43 points · 2 years ago

It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is oriented towards liver disease.

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comment on [Discussion] related substances are doing more work than we give it credit for in c/coa · 212 points · 2 years ago

That is not what the method line says. It names the technique; it does not certify the operator.

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comment on [Question] purity — what am I missing here in c/coa · 40 points · 2 years ago

Pushing back a little: a missing field is usually presentation, not concealment.

Agreed, and the practical version is: ask for the itemised table. If it exists, you get it.

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comment on does telehealth actually matter or is it forum lore at this point in c/compounding · -3 points · 2 years ago

Switched between two compounded preparations and the concentration on the label was different. Redid the arithmetic on paper before drawing anything.

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comment on the lane thing finally clicked for me and I want to write it down in c/intlshipping · 26 points · 2 years ago

Asked QYB which lines they hold regionally before ordering and got a straight list back. Changed what I ordered and when.

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comment on pharmacy — 20 things I got wrong before I got it right in c/glp1eu · 70 points · 2 years ago

Correction: that is the authorisation position, and the question was about reimbursement. Different bodies, different answers.

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comment on small win: sulphur burps stopped being a problem at week 55 in c/sideeffects · 1 points · 2 years ago

sulphur burps are unpleasant and they are not dangerous

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comment on [Lab] 8th independent test on JEEP — 97.2% on a claimed 97.0%, and the trend is the interesting part in c/survodutide · 4 points · 2 years ago

This. Biopsy-confirmed and imaging-suggested are different evidentiary categories and get run together constantly.

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comment on what changed for me between month 8 and month 12 in c/sideeffects · 65 points · 2 years ago

Careful with the supplement recommendation. There is no evidence for it here and the mechanism you are proposing does not hold.

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comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 10 points · 2 years ago

water content is on there and everyone skips it

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comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 43 points · 2 years ago

Sent one vial to Medutest and Janoshik. 99.6% and a claimed 99.0%. Cost me more than the vial and I would do it again.

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comment on how much of what we believe about heart rate actually comes from reflux threads in c/sideeffects · 39 points · 2 years ago

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

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comment on three years of 503B threads, summarised so you do not have to read them in c/compounding · 4 points · 2 years ago

Agreed. The 503A versus 503B distinction changes who is allowed to make what, and almost every confused thread here starts by ignoring it.

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comment on anyone else notice glucagon kicking in around week 47 in c/survodutide · 187 points · 2 years ago

It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is oriented towards liver disease.

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