Housekeeping: the Wegovy rule is doing its job and people should stop complaining. STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is…
u/chidi_demir
Contributes reviews on supplier material. Based in Split.
member · joined 12 Mar 2025
Overview — page 3 of 3
comment on [Meta] proposal — a flair for 503A posts in c/compounding · 50 points · 1 year ago
This. Compounded preparations carry no equivalence claim, and treating them as generics is a category error people make constantly.
comment on [Meta] the Wegovy rule is doing its job and people should stop complaining in c/semaglutide · 5 points · 1 year ago
Correcting myself from earlier in the thread: I said week 4 and it was week 13. Same shape, wrong number.
comment on [Meta] the Wegovy rule is doing its job and people should stop complaining in c/semaglutide · 8 points · 1 year ago
What dose and how many weeks at it before this started?
comment on [Discussion] purity is doing more work than we give it credit for in c/coa · 29 points · 1 year ago
Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.
comment on [Discussion] carrier is doing more work than we give it credit for in c/intlshipping · 251 points · 1 year ago
A lane is an origin, a destination, a carrier and a season. Change any one and the distribution changes, which is why supplier-level shipping averages are close to meaningless.
comment on the prescription thing finally clicked for me and I want to write it down in c/glp1eu · 19 points · 1 year ago
That shortage notice was national and does not apply where the question is coming from.
comment on [Vendor] JEEP vs WXT on the same compound, same month — both cleared 98.5% in c/coa · 1 points · 1 year ago
The PDF creation date being later than the analysis date is usually a re-issue or a re-export.
This is the sentence to take away. The rest of the thread is footnotes to it.
comment on three years of 2.4mg threads, summarised so you do not have to read them in c/semaglutide · 354 points · 1 year ago
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.
comment on 21 months in and semaglutide is still the thing I get wrong in c/semaglutide · 52 points · 1 year ago
Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.
comment on what would you tell week-1 you about gallbladder in c/sideeffects · 69 points · 1 year ago
That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.
21 months in and semaglutide is still the thing I get wrong. Numbers below. Ask me the boring questions, they are the useful ones. To save the first four comments: 21…
comment on three years of water content threads, summarised so you do not have to read them in c/coa · 209 points · 1 year ago
Spent four months confusing area% and mass% in every post I made here. One explainer thread and it clicked permanently.
comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 0 points · 1 year ago
Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.
comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 78 points · 1 year ago
Do sulphur burps track the day after the shot, or is it there all week?
comment on [PSA] Wegovy is not what most of this community thinks it is in c/semaglutide · 43 points · 1 year ago
the first four weeks are a tolerance check, not a weight-loss phase
Wegovy is not what most of this community thinks it is. If you already knew this, the post is not for you and you can scroll on. Steady state after a dose change takes…
comment on help me understand area percent, I have read the wiki twice in c/coa · 193 points · 1 year ago
Ask what the stability statement was written against — temperature, light, and whether it was the lyophilised powder or the reconstituted solution. Those are three different claims.
comment on three years of Apotheke threads, summarised so you do not have to read them in c/glp1eu · 33 points · 1 year ago
Agreed — authorisation is European, reimbursement is national, and almost every confused thread here misses that split.
comment on help me understand lane, I have read the wiki twice in c/intlshipping · 35 points · 1 year ago
That is a packaging observation, not a transit observation. Worth posting, worth separating.
comment on DHL — 21 things I got wrong before I got it right in c/intlshipping · 12 points · 2 years ago
What lead time were you quoted at checkout?
comment on someone explain survodutide to me like I have not read a paper in years in c/survodutide · 14 points · 2 years ago
Read the phase 2 hepatic paper properly and the endpoint definitions were more interesting than the headline response rate.
comment on Apotheke — 10 things I got wrong before I got it right in c/glp1eu · 11 points · 2 years ago
That is an authorisation question and you have answered a reimbursement one. They are decided by different bodies.
comment on transit time — 12 things I got wrong before I got it right in c/intlshipping · 14 points · 2 years ago
A quoted lead time is a commitment you can evaluate. Measuring quoted against actual across several orders tells you more about an operation than the raw speed does.
comment on transit time — 12 things I got wrong before I got it right in c/intlshipping · 55 points · 2 years ago
Push back: comparing a July transit with a February one on the same lane is not a comparison.
comment on why does nobody talk about biopsy in c/survodutide · 43 points · 2 years ago
It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is oriented towards liver disease.
comment on [Discussion] related substances are doing more work than we give it credit for in c/coa · 212 points · 2 years ago
That is not what the method line says. It names the technique; it does not certify the operator.
comment on [Question] purity — what am I missing here in c/coa · 40 points · 2 years ago
Pushing back a little: a missing field is usually presentation, not concealment.
Agreed, and the practical version is: ask for the itemised table. If it exists, you get it.
comment on does telehealth actually matter or is it forum lore at this point in c/compounding · -3 points · 2 years ago
Switched between two compounded preparations and the concentration on the label was different. Redid the arithmetic on paper before drawing anything.
Genuine question, and the title is the question: does telehealth actually matter or is it forum lore at this point. Asked for potency testing on the finished…
comment on the lane thing finally clicked for me and I want to write it down in c/intlshipping · 26 points · 2 years ago
Asked QYB which lines they hold regionally before ordering and got a straight list back. Changed what I ordered and when.
comment on pharmacy — 20 things I got wrong before I got it right in c/glp1eu · 70 points · 2 years ago
Correction: that is the authorisation position, and the question was about reimbursement. Different bodies, different answers.
comment on small win: sulphur burps stopped being a problem at week 55 in c/sideeffects · 1 points · 2 years ago
sulphur burps are unpleasant and they are not dangerous
comment on [Lab] 8th independent test on JEEP — 97.2% on a claimed 97.0%, and the trend is the interesting part in c/survodutide · 4 points · 2 years ago
This. Biopsy-confirmed and imaging-suggested are different evidentiary categories and get run together constantly.
comment on what changed for me between month 8 and month 12 in c/sideeffects · 65 points · 2 years ago
Careful with the supplement recommendation. There is no evidence for it here and the mechanism you are proposing does not hold.
comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 10 points · 2 years ago
water content is on there and everyone skips it
comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 43 points · 2 years ago
Sent one vial to Medutest and Janoshik. 99.6% and a claimed 99.0%. Cost me more than the vial and I would do it again.
comment on how much of what we believe about heart rate actually comes from reflux threads in c/sideeffects · 39 points · 2 years ago
Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.
comment on three years of 503B threads, summarised so you do not have to read them in c/compounding · 4 points · 2 years ago
Agreed. The 503A versus 503B distinction changes who is allowed to make what, and almost every confused thread here starts by ignoring it.
comment on anyone else notice glucagon kicking in around week 47 in c/survodutide · 187 points · 2 years ago
It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is oriented towards liver disease.