Positions 26–50 of 95.
The title is the argument: the endpoint advice in here is 3 years out of date. Here is the rest of it. To save the first four comments: 3 years. On means, which this…
endpoint — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months. Spent an evening with the appendix tables and…
Something I keep coming back to: the STEP question that gets asked weekly, answered properly. Cardiovascular outcome trials are powered for events, not for weight, and…
The title is the argument: SELECT: what the trials say vs what this community says. Here is the rest of it. Intention-to-treat analyses everybody randomised regardless…
Vendor-level purity averages over time, built from independent results rather than vendor claims. Transparent methodology, open dataset.
Browse resultshazard ratio is the most under-discussed thing on this board. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix…
Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from hazard ratio threads. Why comparing…
how much of what we believe about endpoint actually comes from TRIUMPH threads. I would rather ask a basic question now than get this wrong quietly for two months. A…
Posting this as a discussion rather than a claim: SURPASS — 24 things I got wrong before I got it right. Compared myself to a trial mean for about six months before…
why does nobody talk about SELECT. Searched first, found three threads that contradict each other, hence the post. Spent an evening with the appendix tables and found…
Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from SURMOUNT threads. Compared myself to…
someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial…
SURPASS — 14 things I got wrong before I got it right. Making the case below, and I expect to lose some of it in the comments. Quoted a figure here confidently, got…
someone explain FLOW to me like I have not read a paper in years. Searched first, found three threads that contradict each other, hence the post. The discontinuation…
the FLOW rule is doing its job and people should stop complaining. This affects how posts get sorted and removed, so it belongs in the open. The discontinuation numbers…
Posting this as a discussion rather than a claim: SURPASS — 7 things I got wrong before I got it right. Compared myself to a trial mean for about six months before…
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardshow much of what we believe about endpoint actually comes from SELECT threads — that is what I am asking, and I have already read the wiki twice. On means, which this…
SURPASS — 12 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Relative risk reduction without the baseline rate is…
the STEP question that gets asked weekly, answered properly. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix tables…
SURPASS — 6 things I got wrong before I got it right. It is the sort of thing everyone half-believes and nobody writes down. Spent an evening with the appendix tables…
Asking properly rather than in a comment on somebody else’s thread: why does nobody talk about SELECT. Compared myself to a trial mean for about six months before…
the FLOW rule is doing its job and people should stop complaining. Nothing about this affects the ranking maths, before anyone asks. Started keeping the trial…
The title is the argument: TRIUMPH is doing more work than we give it credit for. Here is the rest of it. Went looking for the registered protocol to see whether the…
Asking properly rather than in a comment on somebody else’s thread: does SELECT actually matter or is it forum lore at this point. Compared myself to a trial mean for…
how do you actually verify SURPASS — that is what I am asking, and I have already read the wiki twice. Started keeping the trial identifiers straight in a note file…
the STEP thing finally clicked for me and I want to write it down. Change my mind, genuinely — I have no stake in being right about this. On means, which this board…
Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.
Independent testing plus vendor-level trend data. Community-funded, unaffiliated.
peptidemeter.comSeveral compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.
Reference