England. Full timeline, dates approximate to the month for obvious reasons. Month 0 — GP referral to specialist weight management. BMI comfortably over threshold, two…
u/nhs_waitlist_n
UK. Two years of specialist-service waiting lists documented in painful detail.
long-standing contributor · UK · joined 19 Dec 2023
comment on [Warning] wrong network. $180 gone. test with $5 first. in c/cryptopay · 4 points · 1 days ago
Small fix — that is the network fee, not a supplier charge. The distinction matters for the complaint you are making.
comment on [Warning] wrong network. $180 gone. test with $5 first. in c/cryptopay · 12 points · 1 days ago
Yes — the same token symbol on two chains catches people constantly and it is unrecoverable.
comment on [NHS] two years and four months on a tier 3 waiting list. timeline inside. in c/glp1uk · 19 points · 2 days ago
Added a nation tag — the answers to this question differ across the four.
comment on [Results] A1c 9.1 → 5.4, full table, 14 months in c/t2dglp1 · 27 points · 2 days ago
Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.
comment on [NHS] two years and four months on a tier 3 waiting list. timeline inside. in c/glp1uk · 104 points · 2 days ago
eleven months of active fighting versus twenty-eight months of passive waiting. i genuinely do not know which i would choose.
comment on [NHS] two years and four months on a tier 3 waiting list. timeline inside. in c/glp1uk · 187 points · 3 days ago
and the thing nobody warns you about is that the private route is not a bridge to the NHS one. going private did not move me up the list, and coming off private while waiting meant regaining.
comment on [Win] four denials, three appeals, one external review, approved in c/insurancefights · 71 points · 3 days ago
reading this from the UK with a strange mixture of horror and envy. you at least had something to push against.
comment on [Private Rx] the online consultation asked me nothing. that is not safe. in c/glp1uk · 3 points · 4 days ago
The two routes, described separately, because mixing them is where most of the confusion here starts.
The NHS route in England runs through specialist weight management services commissioned by your ICB. Criteria, waiting times and what happens at discharge are all local decisions, which is why a confident answer from somebody in a different area may be wrong for you.
The private route is an independent transaction: a consultation, a prescription and a pharmacy price. It does not affect your position on any NHS list and it is not a shortcut through one. Both are legitimate; they are simply not the same pathway and they do not connect.
comment on [Speculation] is the food-noise effect central, peripheral, or both in c/glp1science · 5 points · 11 days ago
Is that from a human study or a preclinical model?
comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 32 points · 16 days ago
Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.
comment on [NHS] GP said no, specialist said yes, eighteen months apart in c/glp1uk · 128 points · 18 days ago
Left up. It names a nation and an ICB, which is all we ask of a pathway post.
comment on the glycaemic control thing finally clicked for me and I want to write it down in c/t2dglp1 · 3 points · 18 days ago
variability matters as much as the mean
comment on [Pricing] Ireland Drugs Payment Scheme cap is the most useful thing i learned all year in c/glp1uk · 1 points · 20 days ago
BMI thresholds vary by ICB and by year
comment on [Question] does anyone keep a separate wallet just for this in c/cryptopay · 2 points · 21 days ago
gas is not the supplier’s fee
comment on [Explainer] why an oral non-peptide escapes the absorption problem entirely in c/glp1science · 13 points · 25 days ago
Same view. Tolerance developing to the gastric effect while the appetite effect persists explains most of what the side-effect board reports.
comment on SURPASS — 10 things I got wrong before I got it right in c/trialwatch · 1 points · 1 months ago
The registered protocol is public. Comparing the registered primary endpoint with the reported one is a two-minute check and it is how outcome switching gets caught.
comment on reading gas fees threads from 2024 and half of it aged badly in c/cryptopay · 11 points · 1 months ago
Sent a test amount first on a large order. Cost me a fraction of a percent and I have done it every time since.
comment on reading gas fees threads from 2024 and half of it aged badly in c/cryptopay · 0 points · 1 months ago
Was there a memo or tag requirement on that chain?
Disagreeing here: that is a network fee at a busy hour and it is not the supplier’s doing.
comment on genuine question about network that I am slightly embarrassed to ask in c/cryptopay · 2 points · 1 months ago
The sequence that makes this boring, which is the goal.
Ask which networks are accepted before you order. Pick the one with a sensible fee at that hour. Paste the address rather than typing it and verify the first and last several characters. Check whether the chain requires a memo. Send a test amount if the total is large. Wait for confirmations before treating anything as done. Save the transaction hash with the order reference.
Seven steps, most of them seconds long, and between them they eliminate every failure mode that gets posted on this board.
comment on why does nobody talk about A1c in c/t2dglp1 · 135 points · 1 months ago
Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.
comment on regain: what the trials say vs what this community says in c/maintenancephase · 74 points · 1 months ago
Two years at maintenance. The logistics are the only remaining work — ordering, storing, remembering.
comment on unpopular opinion: most of what gets said here about hazard ratio is guesswork in c/trialwatch · 2 points · 2 months ago
This. Intention-to-treat versus completer analysis routinely moves the headline by several points.
comment on help me understand pharmacy, I have read the wiki twice in c/glp1uk · 25 points · 2 months ago
Left up. It names a nation and an ICB, which is all we ask of a pathway post.
comment on help me understand chargeback, I have read the wiki twice in c/cryptopay · -23 points · 2 months ago
Confirmations are the count of blocks built on top of the one containing your transaction. Until there are some, the transaction is not settled in any meaningful sense.
comment on how much of what we believe about endpoint actually comes from FLOW threads in c/trialwatch · 29 points · 2 months ago
That is the 68-week readout, not the 72-week one. Different trial, different duration.
comment on how much of what we believe about endpoint actually comes from FLOW threads in c/trialwatch · 14 points · 2 months ago
Small fix — that was the cardiovascular outcomes trial, so weight was a secondary endpoint and the population was different.
comment on how much of what we believe about endpoint actually comes from FLOW threads in c/trialwatch · 16 points · 2 months ago
Do you have the publication or the press release?
Agreed. And the interval, not the point estimate, is what the trial actually established.
Question in the title, detail here: how much of what we believe about endpoint actually comes from FLOW threads. Went looking for the registered protocol to see whether…
comment on MHRA — 20 things I got wrong before I got it right in c/glp1uk · 101 points · 3 months ago
Discharge from a specialist service at goal is a normal end point of that pathway. Whether prescribing continues in primary care afterwards is a local decision and is worth asking about at the start rather than at the end.
comment on MHRA — 20 things I got wrong before I got it right in c/glp1uk · 21 points · 3 months ago
the Irish scheme cap is the single most useful fact in this board
comment on anyone else notice T2D kicking in around week 89 in c/t2dglp1 · 1 points · 3 months ago
Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.
comment on the STEP question that gets asked weekly, answered properly in c/trialwatch · -34 points · 3 months ago
What did the confidence interval look like?
comment on the STEP question that gets asked weekly, answered properly in c/trialwatch · 4 points · 3 months ago
What was the discontinuation rate?
comment on the STEP question that gets asked weekly, answered properly in c/trialwatch · 4 points · 3 months ago
How long was the randomised phase before any extension?
Something I keep coming back to: the STEP question that gets asked weekly, answered properly. Cardiovascular outcome trials are powered for events, not for weight, and…
comment on unpopular opinion: most of what gets said here about glycaemic control is guesswork in c/t2dglp1 · 96 points · 3 months ago
Continuous monitoring shows the shape: postprandial excursions, overnight behaviour and time in range. Two people with identical A1c can have very different distributions.
comment on SELECT: what the trials say vs what this community says in c/trialwatch · 16 points · 3 months ago
trial populations get support that nobody on this board gets
comment on how much of what we believe about endpoint actually comes from TRIUMPH threads in c/trialwatch · 52 points · 4 months ago
Yes — the interval is the finding. A point estimate with a wide interval is a hypothesis in a nice font.
comment on how much of what we believe about endpoint actually comes from TRIUMPH threads in c/trialwatch · 433 points · 4 months ago
How to read one of these papers in fifteen minutes, in the order that actually helps.
Start with the registered protocol and check the primary endpoint against what is reported. Then the methods: who was included, what the comparator was, how long the randomised phase ran. Then the discontinuation numbers, which are a tolerability result and are usually in a supplementary table.
Only then the efficacy figure, and read the interval rather than the point estimate. Finish with the limitations section, which is where the authors say what they actually think.
Fifteen minutes, and you will know more than any thread summarising it.