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c/t2dglp1·posted 19 days ago by u/nadia_norgaard

the glycaemic control thing finally clicked for me and I want to write it down

Caution The Quiet One ×9

the glycaemic control thing finally clicked for me and I want to write it down. Making the case below, and I expect to lose some of it in the comments.

My TSH moved and it turned out to have nothing to do with glucose at all.

Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.

Assumed the weight endpoints from the obesity trials applied to my situation. They are different programmes.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

184 up / 279 down40% upvoted12 commentsid 1q8pnf10 Jul 2026

12 comments

12 in this archive, depth 3

best — the order this archive was captured in

u/marisol_moreau11 points·18 days ago

Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.

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u/farid_jansen2 points·18 days ago

Sensor accuracy varies across wear, and readings on the first day are the least reliable.

Agreed, and the glucose-dependence point is the reason the risk profile reads the way it does.

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u/long_post_larry2 points·18 days ago

the fasting number is the one people fixate on and it moves last

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u/fasting_insulin_fMOD7 points·19 days ago

Identifying details redacted from the exported report above.

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u/nadia_norgaardOP4 points·18 days ago

Identifying details redacted from the exported report above.

Adding the obvious one — bring the export, not the single number, to whoever manages this.

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u/nadia_norgaardOP4 points·18 days ago·edited

What else is in the regimen?

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u/lucia_balogun6 points·18 days ago

Not convinced. Hypoglycaemia risk from this class alone is low; the risk you are describing comes from the combination.

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u/nhs_waitlist_nUK3 points·18 days ago

variability matters as much as the mean

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u/gustav_lindholm3 points·18 days ago

Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.

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u/baseline_drifteranalytical1 point·18 days ago·edited

The order things move in, since nobody explains it and it worries people.

Postprandial excursions generally respond earliest. Variability tends to narrow before the average does, which is visible on a sensor and invisible on a lab result. Fasting glucose is often the laggard, and A1c — being a three-month average — is the last thing to reflect anything.

So a month in which the sensor looks better and the fasting number has not moved is the ordinary sequence, not a contradiction. Knowing that in advance would have saved me a quarter of unnecessary worry, which is why it is worth writing down.

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u/marit_mwangi1 point·17 days ago

Is that a first-day sensor reading?

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u/stubborn_batchlist_maybe1 point·17 days ago

I would not compare your numbers to that population. Different baseline, different regimen, different trial.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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