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c/tapering·posted 8 months ago by u/dario_stanescu

the regain question that gets asked weekly, answered properly

Results Well Actually ×1 Cold Box ×2

the regain question that gets asked weekly, answered properly — a position I have arrived at slowly and would like tested.

Regained most of it over a year and spent that year assuming it was my fault. It was not; it is what the literature describes.

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

1,904 up / 384 down83% upvoted19 commentsid kd49b11 Dec 2025

19 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/arne_restrepo0 points·8 months ago

Appetite is the proximal effect and weight is the lagging integrated outcome, which is why watching appetite gives you an earlier and more honest signal.

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u/injection_site_iris232 points·7 months ago

Why the first fortnight tells you nothing.

With a week-long half-life, exposure declines over several weeks after a final dose rather than ending with it. So the first two weeks after stopping are still a tail of the previous state, and the stability people report in that window is not evidence about the months after it.

The reports here are fairly consistent: appetite noticeably different somewhere in the second month, weight following later, and the trajectory strongly influenced by whether the habits from the losing phase survived. That is not a prediction for anybody in particular, and it is not a schedule — it is the shape of what members describe, which is the most this board can honestly offer.

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u/viktor_kirchner129 points·8 months ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

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u/chain_confirm_cpayments73 points·8 months ago

have the conversation with a clinician before, not after

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u/marta_marchand28 points·7 months ago

Correction: that study measured regain after discontinuation, not loss of effect during treatment. Very different findings.

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u/maintenance_mode_maxMOD67 points·8 months ago

Edited a comment framing regain as a moral failure. The documented outcome is not a character verdict.

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u/elin_varga-7 points·7 months ago

stopping is a plan, not an event

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u/dario_stanescuOP1 point·7 months ago

Small fix — you have described interval stretching and called it a taper. The exposure profiles differ.

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u/lane_watchermod · logistics0 points·7 months ago

That is a pause rather than a stop, and the plans for the two are not the same.

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u/dario_stanescuOP1 point·7 months ago

Correcting myself upthread: appetite returned at week 8 for me, not the week I posted.

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u/andres_restrepo1 point·7 months ago

decide what you are watching for before you stop

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u/viktor_laurent1 point·7 months ago·edited

That reads as advice to stop, which is not something anyone here should be offering.

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u/dario_stanescu1 point·7 months ago

write down where you are before you change anything

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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