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Single comment threadYou are looking at one branch of three years of appetite return threads, summarised so you do not have to read them — 28 comments in the full submission. View in context.
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c/tapering·submitted 1 year ago by u/taper_off_tabitha

three years of appetite return threads, summarised so you do not have to read them

Trial Databranch of 6 comments

Thinking out loud about this: three years of appetite return threads, summarised so you do not have to read them. Went back on after eight months away. Nobody here made me feel bad about it, which mattered more than I expected. Had the conversation with a clinician before stopping rather than after. Considerably…

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6 comments, started 1 year ago
u/taper_off_tabitha51 points·1 year ago

What the evidence says about stopping, written plainly because the framing does real damage.

Withdrawal studies across this class consistently show substantial regain after discontinuation. Appetite typically returns first, well before weight changes. This is a finding about the pharmacology of a chronic condition, in the same way that blood pressure rises again when an antihypertensive is stopped.

People on this board quit in shame over an entirely predictable result, and then avoid coming back because they have interpreted it as a personal failure. It is not. Knowing that in advance is the single most useful thing this board can offer anybody planning to stop.

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u/coldchain_karencold chain42 points·1 year ago

What the evidence says about stopping, written plainly because the framing does real damage.

This is the sentence that reframes the whole board. Appetite first, scale later.

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u/quiet_reader_9914 points·1 year ago

coming back later is allowed and it is common

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u/ilias_kaufmann15 points·1 year ago

Stretched from seven days to ten to twelve over four months. Appetite told me where the limit was each time.

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u/ignacio_silva4 points·1 year ago

Push back: that is a taper schedule aimed at another member and this board does not host those.

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u/taper_off_tabithaOP22 points·1 year ago

a fortnight of nothing is not evidence that you are fine

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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