[PSA] T2D is not what most of this community thinks it is
T2D is not what most of this community thinks it is — with the reasoning, because a rule without a reason gets ignored. The diabetes and obesity programmes are separate, with different populations and different primary endpoints. Reading a result across from one to the other is not a comparison. Incretin-based agents…
Sensor accuracy varies across wear, and readings on the first day are the least reliable. Calibration practice and compression artefacts explain many alarming single values.
Sensor accuracy varies across wear, and readings on the first day are the least reliable.
santiago_rasmussen is right that the fasting number moves last. Knowing that in advance saves months of worry.
a single high reading is not a trend
Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.
A1c is a three-month average and it lags everything
Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.
check the trial population before quoting a result at somebody
Cosigning that postprandial excursions improve first and the fasting number is the laggard.
Agreed on variability. Two people with the same average can have completely different days.
Agreed on variability.
Disagreeing with this line: that endpoint is from the obesity programme and does not answer the question.
How long between the two A1c measurements?
Right, and the diabetes programmes report glycaemic endpoints. Quoting an obesity trial result here is answering a different question.
Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.
A1c, CGM, or fingersticks — which are we discussing?
Assumed the weight endpoints from the obesity trials applied to my situation. They are different programmes.