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my A1c moved and I cannot work out whether reflux is why

Discussion Cold Box ×7 Long Haul ×2 Receipts ×2

The title is the argument: my A1c moved and I cannot work out whether reflux is why. Here is the rest of it.

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 37 probably does not, and that is worth saying to a clinician rather than to us.

Please do not ask me what dose you should be on. I genuinely do not know and neither does anyone else here.

5,672 up / 914 down86% upvoted48 commentsid o9m1yj9 Sep 2024

48 comments

16 in this archive, depth 5

best — the order this archive was captured in

u/lina_dziedzic-11 points·1 year ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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[deleted]1 point·1 year ago

[deleted]

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u/rina_bergstrom472 points·1 year ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/tomas_lehtinen382 points·1 year ago

the food noise going quiet is the effect people came for, and reflux is the toll for the first fortnight

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u/chidi_abubakar381 points·1 year ago

hair shedding follows the weight loss, not the drug, and it stops

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u/graph_it_gary391 points·1 year ago

nausea on day two and gone by day four is the standard shape

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u/leila_silva107 points·1 year ago

Cosigning the fibre and water answer. Unglamorous, free, and it fixed it for me inside a week.

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u/rekha_mbeki327 points·1 year ago

nobody warns you about how much of this is timing rather than dose

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u/nausea_notesMOD217 points·1 year ago

Removed the specific recommendation. Describe your own experience here; do not tell another member what to take or what dose to be on.

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u/rania_marchand104 points·1 year ago

Yes. Holding the dose is a real option and it does not mean you have failed at anything.

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u/idris_iyer59 points·1 year ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/reta_and_regret35 points·1 year ago

Are you eating in the couple of hours before you sleep?

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u/ferran_dahlberg12 points·1 year ago

fibre and water before you buy anything to fix it

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u/signe_villalobos86 points·1 year ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

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u/vendorinvestigate_vicOP65 points·1 year ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/aleksi_lehtinen48 points·1 year ago

Correction: that is a known effect of reduced intake rather than a direct drug effect. The distinction matters because the fix is different.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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