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c/sideeffects·submitted 1 year ago by u/zeynep_ndiaye

[Discussion] reflux is doing more work than we give it credit for

Discussionbranch of 10 comments

reflux is doing more work than we give it credit for. It is the sort of thing everyone half-believes and nobody writes down. The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.…

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10 comments, started 1 year ago
u/chidi_demir949 points·1 year ago

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

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u/zeynep_ndiayeOP391 points·1 year ago

if it is severe or persistent that is a clinician question, not a board question

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u/liv_vukovic320 points·1 year ago

That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.

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[deleted]209 points·1 year ago

[deleted]

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u/quiet_moderatormod56 points·1 year ago

Disagree. Severe abdominal pain is not on the list of things to wait out, and this board should not be treating it as one.

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u/ayesha_radich617 points·1 year ago

Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.

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u/enzo_danquah514 points·1 year ago

This. A bad fortnight after a step is expected. A bad quarter is a reason to talk to somebody who knows your history.

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u/elin_trevino162 points·1 year ago

the first fortnight after a step is the worst of it, then it settles

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u/emil_barros422 points·1 year ago

This.

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/zeynep_ndiayeOP0 points·1 year ago

Correction: that is a known effect of reduced intake rather than a direct drug effect. The distinction matters because the fix is different.

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