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c/sideeffects·posted 2 years ago by u/diego_sorensen

week 52 check-in — 14kg down, reflux manageable, one thing confusing me

Side Effects Cold Box ×1 Sourced ×2 Well Actually ×2

week 52 check-in — 14kg down, reflux manageable, one thing confusing me, and the part I actually want to talk about is at the bottom.

Pulling the figures out of the title: week 52 and 14kg. All of it is written down as it happened rather than reconstructed.

Keeping a log, and what to put in it.

One line a day: dose, day since injection, what the symptom was and how bad out of five, and roughly what you ate. Two months of that fits on one page and the pattern is obvious on paper in a way it never is in your head.

Mine showed a clean day-two-to-day-four window I had been describing as "random". Once you can see the pattern you can plan around it, and planning around it is most of the relief.

On buying things to fix side effects, which I did extensively and would not do again.

The interventions that changed anything for me were all behavioural and free: smaller meals, eating slower, stopping food a few hours before sleep, more fibre and considerably more water. The things I bought did nothing I could detect, and I was motivated to detect something.

The other lever, which people forget, is time at dose. Holding rather than stepping is a legitimate plan and it fixed my tolerance where nothing else did.

Happy to answer the boring questions. Those are usually the ones worth asking.

12,583 up / 9,175 down58% upvoted50 commentsid 1jcjun7 Dec 2023

50 comments

20 in this archive, depth 4

best — the order this archive was captured in

u/zeynep_zielinski419 points·2 years ago

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 25 probably does not, and that is worth saying to a clinician rather than to us.

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[deleted]150 points·2 years ago

[deleted]

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u/reta_and_regret51 points·2 years ago

Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.

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u/marta_marchand28 points·2 years ago

How long has it been going on for now?

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u/emil_barros34 points·2 years ago

Pushback: you changed the dose, the meal timing and the training in the same fortnight, so the attribution is guesswork.

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u/chidi_demir23 points·2 years ago

That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.

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u/iman_falk51 points·2 years ago

Agreed on writing it down. I could not see the pattern until I had six weeks of it on one page.

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u/ferritin_low135 points·2 years ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/liv_okafor176 points·2 years ago

Has anything else changed in the same window?

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u/signe_villalobos357 points·2 years ago·edited

Disagree. Severe abdominal pain is not on the list of things to wait out, and this board should not be treating it as one.

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u/karma_irrelevant-7 points·2 years ago

The pattern almost everyone here describes, written out once so it can be linked.

A step up is followed by a rough window — commonly food noise arriving the day after the shot and easing by day four, worst in the first fortnight, then flattening out. At a stable dose it usually settles further. Constipation and fatigue tend to track intake and fluid rather than the compound directly, which is why the unglamorous answers work.

What sits outside that pattern: severe pain, symptoms that appear from nowhere weeks into a stable dose, or anything getting worse rather than better over a month. None of that is a board question and none of us can answer it for you.

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u/wrong_network_w1 point·2 years ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/fabio_nkemelu1 point·2 years ago

write down when it starts and stops, the pattern is the useful part

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u/rafael_ostergaard1 point·2 years ago

if it is severe or persistent that is a clinician question, not a board question

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u/ferran_dahlberg-8 points·2 years ago

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

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u/liv_okafor1 point·2 years ago

How long after a step up did this start?

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u/peptidemeter_pat1 point·2 years ago

eating slower does more than most of the supplements people recommend

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u/liv_vukovic1 point·2 years ago·edited

eating slower does more than most of the supplements people recommend

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/chidi_abubakar1 point·2 years ago

Not convinced by that mechanism. Slowed gastric emptying explains fullness and reflux; it does not explain what you are describing.

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u/ahmed_rasmussen156 points·2 years ago·edited

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

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Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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