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c/semaglutide·submitted 5 months ago by u/yara_boateng

[Question] how do you actually verify Ozempic

Questionbranch of 9 comments

Asking properly rather than in a comment on somebody else’s thread: how do you actually verify Ozempic. The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals. Kept a log from week one and the single most useful column turned out to be waist, not…

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9 comments, started 5 months ago
u/ravi_bergstrom63 points·5 months ago

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

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u/slow_logbook_notes14 points·5 months ago

STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure

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u/yara_boatengOP10 points·5 months ago

STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure

Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.

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u/enzo_danquah0 points·5 months ago

Do muscle cramps track the day after the shot, or is it there all week?

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u/ahmed_abubakar1 point·5 months ago

protein first, then everything else gets easier

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u/marit_coelho1 point·5 months ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/helga_vermeulen1 point·5 months ago

if 0.25mg is working there is no prize for going up

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u/meta_analysis_mo1 point·5 months ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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u/yara_boatengOP1 point·5 months ago

food noise made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it.

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