14 months in and titration is still the thing I get wrong
Here it is: 14 months in and titration is still the thing I get wrong. One person, one log, no control group, so read it accordingly. Hard numbers: 14 months. Anything softer than that is flagged as an impression. What I would tell week-one me, in order of how much time it would have saved. One: the first month is a…
Correct, and worth adding: the trial average is an average. Half the people in it did worse than 15% and were still on the drug.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.
Weight change and appetite change are different endpoints on different timescales.
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the early fullness usually fades at a stable dose.
Week 95: 25kg down, fatigue basically gone since about week 7, and the honest headline is that nothing dramatic happened. It was boring and it worked.