stopped losing at 1.7 so i went to 2.4 and lost nothing faster
stopped losing at 1.7 so i went to 2.4 and lost nothing faster. Change my mind, genuinely — I have no stake in being right about this.
STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the early fullness usually fades at a stable dose.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
best — the order this archive was captured in
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
Standard reminder: no personal titration plans for other members, and no medical advice. Everything else is fine.
Standard reminder: no personal titration plans for other members, and no medical advice.
units_not_mg is describing the standard shape here and it matches the trial data better than most anecdotes do.
That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.
My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.