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c/semaglutide·submitted 11 months ago by u/hassan_castellanos

[Discussion] we are measuring food noise at the wrong time and calling it noise

Discussionbranch of 6 comments

we are measuring food noise at the wrong time and calling it noise. Making the case below, and I expect to lose some of it in the comments. injection-site soreness made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it. Dropped my injection day by two…

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6 comments, started 11 months ago
u/enzo_danquah215 points·11 months ago

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.

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[removed]87 points·11 months ago

[removed by moderator]

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u/endpoint_creep49 points·11 months ago

Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.

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u/hassan_castellanosOP18 points·11 months ago

Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.

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u/alcohol_aversion127 points·11 months ago

How long was the stall before you decided it was a stall?

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u/plain_titration187 points·11 months ago

How long was the stall before you decided it was a stall?

Disagree with this specific line. A pause at 0.5mg is not evidence that 0.5mg has stopped working.

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