week 2 and literally nothing has happened, is this normal
week 2 and literally nothing has happened, is this normal, logged the same way every week so the comparison is at least internally fair.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the constipation usually fades at a stable dose.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
best — the order this archive was captured in
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.
This matches me almost exactly, right down to the food noise showing up on the second day and being gone by the fourth.
Yes. Week 89 is when almost everybody writes the "is it still working" post, and almost everybody is fine.