STEP 1 was -14.9% average and i keep having to remind myself average means average
Filing this under things worth writing down: STEP 1 was -14.9% average and i keep having to remind myself average means average.
Numbers, in the order they matter: 14.9%.
First month I lost almost nothing and nearly quit. Month two and three were where it all happened.
The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.
Would rather be corrected in public than confident in private.
best — the order this archive was captured in
Leaving this up. It is a check-in, it has numbers, and it is honest about being one person.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.
What did week 34 look like compared with this one? The month either side is the useful comparison.
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the constipation usually fades at a stable dose.
STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.
Sat at 0.25mg for four months because it was doing the job. Everyone told me to go up. The one time I did, the only thing that changed was the sulphur burps.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
Same. I sat at 1.7mg for three months because it was working and there was nothing to fix.
I would push back gently. Going up because the scale paused is the single most common mistake described on this board.
Does food noise track the day after the shot, or is it there all week?
Did protein intake change in the same window?
Did protein intake change in the same window?
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.