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c/semaglutide·submitted 1 year ago by u/source_or_silence

the weekly dosing thing finally clicked for me and I want to write it down

Discussionbranch of 9 comments

the weekly dosing thing finally clicked for me and I want to write it down, which sounds obvious until you try to state the evidence for it. The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does…

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9 comments, started 1 year ago
u/reflux_report305 points·1 year ago

Yes. Week 86 is when almost everybody writes the "is it still working" post, and almost everybody is fine.

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u/source_or_silenceOP445 points·1 year ago

the first four weeks are a tolerance check, not a weight-loss phase

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u/kavya_radich363 points·1 year ago

Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.

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u/adaeze_brandt498 points·1 year ago

the food noise going quiet is the effect people actually describe

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u/archived_thread_a149 points·1 year ago

Same injection day each week, or has it drifted?

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u/endpoint_creep-1 point·1 year ago

do not chase somebody else’s titration schedule, they are not you

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u/rina_bergstrom1 point·1 year ago

dose day drift of a day either way is fine, the curve barely notices

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u/plain_titration1 point·1 year ago

protein first, then everything else gets easier

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u/reflux_report1 point·1 year ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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