[Results] 21 weeks, 9kg, and plateau was the hard part
21 weeks, 9kg, and plateau was the hard part. Posting the boring middle of the process, because the internet is full of the start and the end and nothing else. Numbers, in the order they matter: 21 weeks and 9kg. STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a…
On the "everybody ends up at 2.4" claim, which comes up every few weeks.
The escalation schedule in the trials was designed to get people to a fixed study dose. Real use is not a trial. The dose that keeps your appetite quiet with side effects you can live with is the dose, and for a lot of people on this board that has been 0.25mg for a very long time.
The counter-argument, which is fair: some people genuinely do need the top of the range, and staying low out of caution costs them months. That is a conversation with someone who knows your history, not with us.
Agreed, and the bit people skip is that the ladder is a tolerance ladder. It is not a potency ranking.
stalling at 0.25mg is information, not a verdict
Week 60: 29kg down, injection-site soreness basically gone since about week 10, and the honest headline is that nothing dramatic happened. It was boring and it worked.
The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.
Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.