[Meta] the 2.4mg rule is doing its job and people should stop complaining
the 2.4mg rule is doing its job and people should stop complaining, and it will stay as it is unless somebody makes the case to change it. The numbers the title promised, since a headline without them is worthless: 2.4mg. Everything below is context for those. Research-use-only material is not approved for human use,…
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.
Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.
That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.
Cosigning. The appetite change and the scale change ran about three weeks apart for me too.
Do sulphur burps track the day after the shot, or is it there all week?
protein first, then everything else gets easier
staying at 2.4mg for an extra month is a legitimate plan