titration — my 23-week log, condensed into one table
titration — my 23-week log, condensed into one table. Making the case below, and I expect to lose some of it in the comments. injection-site soreness made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it. Dropped my injection day by two days once…
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.
Sat at 1.7mg for four months because it was doing the job. Everyone told me to go up. The one time I did, the only thing that changed was the fatigue.
That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.
STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure
Small correction: 2.4mg is the maintenance ceiling on the label, not the starting maintenance dose. The distinction matters for anyone reading this later.
STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure
This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.