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u/swirl_dont_shake

You are not making a cocktail. Roll it between your palms.

long-standing contributor · reconstitution · joined 16 Jan 2024

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comment on [PSA] your bac water is fine, your fridge door is not in c/reconstitution · 48 points · 2 days ago

10mg into 3mL is 3.33mg/mL, and 2.5mg of that is 75 units

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comment on [Math] 10mg vial + 2mL bac water, i want 2.5mg, how many units in c/reconstitution · 119 points · 2 days ago

What concentration did you actually reconstitute at, rather than what did you intend to?

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comment on is the tirz appetite thing actually different or am i imagining it in c/tirzepatide · 1 points · 2 days ago

Which week did the appetite change actually land for you?

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comment on asked my compounder where the API comes from. long silence. in c/compounding · 35 points · 3 days ago

A 503A pharmacy compounds for an identified patient against a prescription. A 503B outsourcing facility registers with the regulator, may produce without patient-specific prescriptions, and is subject to current good manufacturing practice requirements. The two are governed differently and the difference is not cosmetic.

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comment on what does titration actually mean in c/newbiequestions · 17 points · 4 days ago

Small correction, said kindly: those are two different products with similar names, and the difference matters for a multi-draw vial.

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comment on sterile water is not bacteriostatic water and it is not close in c/reconstitution · 73 points · 6 days ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on why does GIP agonism seem to reduce nausea rather than add to it in c/glp1science · 11 points · 8 days ago

Do you have the paper, or a summary of it?

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comment on [Discussion] we use "appetite suppression" to describe three different mechanisms in c/glp1science · 4 points · 9 days ago

Do you have the paper, or a summary of it?

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comment on [PSA] a vendor-supplied COA is a marketing document until someone else agrees with it in c/vendorvetting · 1 points · 10 days ago

reship policy in writing before the order, not after

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comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 11 points · 12 days ago

Yes — time in range tells you about variability, which the average deliberately hides.

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comment on [Vendor] BCH — twelve certificates, twelve with batch, date, method and water content in c/vendorvetting · 3 points · 12 days ago

Careful. "Nobody has tested Paradigm Peptide" is a statement about this board, not about the supplier. Say the first thing, not the second.

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comment on [Question] does anyone get a COA from their compounding pharmacy in c/compounding · 29 points · 14 days ago

compounded is not generic, there is no equivalence claim

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comment on [Question] does anyone get a COA from their compounding pharmacy in c/compounding · 4 points · 14 days ago

Concentration on the compounded vial was different from what I had been using and I nearly did the arithmetic on autopilot.

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comment on [PSA] let the alcohol swab dry before you puncture, that is the step everyone skips in c/reconstitution · 70 points · 14 days ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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comment on help me understand insulin syringe, I have read the wiki twice in c/reconstitution · 2 points · 20 days ago

Same. I got this wrong once, caught it because the units looked absurd, and have written on every vial since.

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comment on [Data] packaging quality by vendor, scored on five things, 60 shipments in c/intlshipping · 2 points · 22 days ago

Yes — median rather than best case.

annika_fonseca is right about regional stock. It changes the shape of the distribution, not just the mean.

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comment on [Unverified] anyone else get a DM offering "wholesale pricing" in c/scamalerts · 6 points · 25 days ago

if the price is impossible, the material is the thing being economised on

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comment on what is the difference between compounded and the pen in c/newbiequestions · 1 points · 27 days ago

What week are you in?

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comment on [Vendor] MKM — five tests, four compounds, nothing outside the band in c/vendorvetting · 30 points · 1 months ago

Yes. Spread across lots is the number that tells you about the process. A single high result tells you about a vial.

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comment on [Results] 65 weeks on 15mg, full numbers, ask me anything boring in c/tirzepatide · 2 points · 1 months ago

Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.

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comment on silly question but which day of the week should i pick in c/newbiequestions · 18 points · 1 months ago

Has the appetite changed, even if the scale has not?

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comment on [Question] France — has anyone got a straight answer on telehealth in c/compounding · 91 points · 1 months ago

Correction: patient-specific refers to the prescription, not to a bespoke formulation. Common misreading and it changes the argument.

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comment on [Confirmed] site copied our own wiki text word for word to look legitimate in c/scamalerts · 5 points · 1 months ago

The directory deliberately separates "we have nothing on this name" from "this went badly". Collapsing the two is how boards like this generate false certainty.

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comment on [Confirmed] site copied our own wiki text word for word to look legitimate in c/scamalerts · 7 points · 1 months ago

Agreed. The clone copies the front page and never the paperwork, because the paperwork is the expensive part.

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comment on 23 months in and week one is still the thing I get wrong in c/newbiequestions · 12 points · 1 months ago

I would not panic about that. It is on the list of ordinary first-month experiences.

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comment on [Discussion] the bacteriostatic water advice in here is 3 years out of date in c/reconstitution · 1 points · 1 months ago

Left up and flaired Explainer — the numbers in this one check out.

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comment on [Meta] the 503A rule is doing its job and people should stop complaining in c/compounding · 31 points · 1 months ago

Right, and the concentration genuinely can differ from the branded product, which breaks people’s arithmetic.

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comment on [Question] how do you actually verify first time in c/newbiequestions · 4 points · 1 months ago

Gently disagree with the framing — nothing has gone wrong. Week 19 looking flat is the ordinary experience.

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comment on three years of pharmacology threads, summarised so you do not have to read them in c/glp1science · 1 points · 2 months ago

a mechanism you can state is not a mechanism you have demonstrated

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comment on nobody warned me about muscle cramps and I would have liked the warning in c/tirzepatide · 106 points · 2 months ago

2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.

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comment on incretin: what the trials say vs what this community says in c/glp1science · 1 points · 2 months ago

tolerance to the gastric effect develops, appetite effect largely persists

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comment on unpopular opinion: most of what gets said here about glycaemic control is guesswork in c/t2dglp1 · -21 points · 3 months ago

How long between the two A1c measurements?

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comment on unpopular opinion: most of what gets said here about glycaemic control is guesswork in c/t2dglp1 · 75 points · 3 months ago

hypoglycaemia risk depends far more on what else you take

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comment on unpopular opinion: most of what gets said here about glycaemic control is guesswork in c/t2dglp1 · 121 points · 3 months ago

Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.

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comment on the units question that gets asked weekly, answered properly in c/reconstitution · 21 points · 3 months ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

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comment on how much of what we believe about bacteriostatic water actually comes from dead space threads in c/reconstitution · 182 points · 4 months ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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comment on help me understand receptor, I have read the wiki twice in c/glp1science · 189 points · 4 months ago

Long half-life in this class comes from structural modification that promotes albumin binding and resists enzymatic degradation. Weekly dosing is a consequence of the molecule, not a convenience decision.

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comment on [Lab] 4th independent test on JEEP — 97.3% on a claimed 97.0%, and the trend is the interesting part in c/tirzepatide · 3 points · 4 months ago

Cosigning the four-week thing. It is a minimum interval, and treating it as a schedule to keep up with is how people end up miserable at 12.5.

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comment on how much of what we believe about 503A actually comes from telehealth threads in c/compounding · 1 points · 4 months ago

503A or 503B — do you know which?

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comment on [PSA] Zepbound is not what most of this community thinks it is in c/tirzepatide · 35 points · 4 months ago

Did you come to this from sema, and if so how long was the gap?

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