is the tirz appetite thing actually different or am i imagining it
is the tirz appetite thing actually different or am i imagining it. If this has been answered properly somewhere, link me and I will delete.
Switching from semaglutide, since three people asked in this thread alone.
There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.
None of that is a recommendation. It is what the threads say, and the threads are not a clinic.
Week 61 was the first time the scale moved after a five-week stall. I changed nothing in that window.
Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
best — the order this archive was captured in
The four-week interval in the label is a minimum. Nothing about the pharmacology requires you to step on schedule, and the trials stepped on a calendar because trials have to.
What step are you on and how long have you been there?
I would separate the two claims. That the GIP arm exists is uncontroversial; that it explains your food noise pattern is a guess.
What step are you on and how long have you been there?
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
a lot of people plateau nicely at 10mg and never need 15
Correction to my own post above — I said 15mg and I have been on 5mg since the spring. Same argument, wrong number.
switching from sema is not a dose conversion, there is no clean equivalence
2.5 is the starter dose and it is not meant to be the dose that works
2.5 is the starter dose and it is not meant to be the dose that works
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.
[deleted]
Which week did the appetite change actually land for you?
switching from sema is not a dose conversion, there is no clean equivalence
Saving this one. It is the clearest statement of the stall problem I have read here.
This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.
This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.
dexa_twice_yearly is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
Disagree with the conversion table. There is no validated equivalence between the two molecules and posting one as though there is does real damage.
- 1switching from sema is not a dose conversion, there is no clean equivalence7 comments in this branch · started by u/hub_ops
- 2The four-week interval in the label is a minimum. Nothing about the…6 comments in this branch · started by u/noor_hovland