[Results] 65 weeks on 15mg, full numbers, ask me anything boring
Check-in as promised in the title: 65 weeks on 15mg, full numbers, ask me anything boring.
The relevant figures are 65 weeks and 15mg, and they come from the same log I have kept the whole time.
The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.
Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.
That is everything I have. The rest is opinion and I have tried to keep it out.
best — the order this archive was captured in
The step schedule question, answered properly, because it comes up weekly.
The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may go, and it exists because tolerability, not efficacy, is what limits most people. There is nothing in the pharmacology that says you must increase at four weeks, or at eight, or ever.
What decides it in practice is whether the effect you want is still there. If appetite is quiet and the trend is going the right way, the dose is doing its job. If both have genuinely gone flat for six weeks or more, that is a conversation worth having with someone who knows your history.
6kg over 25 weeks, never went past 10mg, and reflux stayed mild the whole way. Posting because the loud threads are all 15mg.
2.5 is the starter dose and it is not meant to be the dose that works
the trials titrated on a calendar, real people titrate on symptoms
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
Cosigning the four-week thing. It is a minimum interval, and treating it as a schedule to keep up with is how people end up miserable at 12.5.
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What is the waist doing? That is usually the number still moving during a scale stall.
if 7.5 is working, 10 is not automatically better
zepbound and mounjaro are the same compound with different labels
Correction to my own post above — I said 5mg and I have been on 2.5mg since the spring. Same argument, wrong number.
Correction to my own post above — I said 5mg and I have been on 2.5mg since the spring.
elin_ferrari is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.
Not sure that follows. You went up a step and changed your training in the same fortnight.
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
Not sure that follows.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Are you comparing yourself with the trial mean or with the people who post the most?
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.
Which week did the appetite change actually land for you?
the four-week step schedule is the label, not folklore
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.
week 7 is early to draw any conclusion at all
sulphur burps are the signature complaint and they are not dangerous
sulphur burps are the signature complaint and they are not dangerous
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.
Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate.
- 1The step schedule question, answered properly, because it comes up weekly.…16 comments in this branch · started by u/alcohol_aversion
- 2Are you comparing yourself with the trial mean or with the people who post…8 comments in this branch · started by u/emil_okwuosa