Question in the title, detail here: how much of what we believe about endpoint actually comes from FLOW threads. Went looking for the registered protocol to see whether…
c/trialwatch — new, page 2
Positions 26–50 of 95.
the STEP thing finally clicked for me and I want to write it down. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix…
The title is the argument: the endpoint advice in here is 3 years out of date. Here is the rest of it. To save the first four comments: 3 years. On means, which this…
endpoint — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months. Spent an evening with the appendix tables and…
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glbiochem.netSomething I keep coming back to: the STEP question that gets asked weekly, answered properly. Cardiovascular outcome trials are powered for events, not for weight, and…
The title is the argument: SELECT: what the trials say vs what this community says. Here is the rest of it. Intention-to-treat analyses everybody randomised regardless…
hazard ratio is the most under-discussed thing on this board. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix…
Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from hazard ratio threads. Why comparing…
how much of what we believe about endpoint actually comes from TRIUMPH threads. I would rather ask a basic question now than get this wrong quietly for two months. A…
Posting this as a discussion rather than a claim: SURPASS — 24 things I got wrong before I got it right. Compared myself to a trial mean for about six months before…
why does nobody talk about SELECT. Searched first, found three threads that contradict each other, hence the post. Spent an evening with the appendix tables and found…
Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from SURMOUNT threads. Compared myself to…
someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial…
SURPASS — 14 things I got wrong before I got it right. Making the case below, and I expect to lose some of it in the comments. Quoted a figure here confidently, got…
someone explain FLOW to me like I have not read a paper in years. Searched first, found three threads that contradict each other, hence the post. The discontinuation…
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Browse resultsthe FLOW rule is doing its job and people should stop complaining. This affects how posts get sorted and removed, so it belongs in the open. The discontinuation numbers…
Posting this as a discussion rather than a claim: SURPASS — 7 things I got wrong before I got it right. Compared myself to a trial mean for about six months before…
how much of what we believe about endpoint actually comes from SELECT threads — that is what I am asking, and I have already read the wiki twice. On means, which this…
SURPASS — 12 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Relative risk reduction without the baseline rate is…
the STEP question that gets asked weekly, answered properly. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix tables…
The title is the whole question — help me understand SURMOUNT, I have read the wiki twice — but here is why I am asking. Discontinuation rates are a tolerability…
SURPASS — 6 things I got wrong before I got it right. It is the sort of thing everyone half-believes and nobody writes down. Spent an evening with the appendix tables…
Asking properly rather than in a comment on somebody else’s thread: why does nobody talk about SELECT. Compared myself to a trial mean for about six months before…
the FLOW rule is doing its job and people should stop complaining. Nothing about this affects the ranking maths, before anyone asks. Started keeping the trial…
The title is the argument: TRIUMPH is doing more work than we give it credit for. Here is the rest of it. Went looking for the registered protocol to see whether the…