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c/trialwatch·submitted 2 years ago by u/alcohol_aversion

SELECT: what the trials say vs what this community says

Trial Databranch of 6 comments

SELECT: what the trials say vs what this community says — a position I have arrived at slowly and would like tested. Why comparing across trials almost never works, with the specific failure modes. Different populations: an obesity programme and a diabetes programme enrol different people with different baseline…

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6 comments, started 2 years ago
u/hazard_ratio_halMOD122 points·2 years ago

Added the trial identifier to the title so this thread is findable in two years.

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u/zaid_roos98 points·2 years ago

Correction: SURMOUNT is the obesity programme and SURPASS is the diabetes one. The figure you quoted belongs to the other one.

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u/hedda_adeyemi29 points·2 years ago

SELECT was cardiovascular outcomes, not weight

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[removed]19 points·2 years ago

[removed by moderator]

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u/alcohol_aversionOP52 points·2 years ago

Argued for a week about a result and then read the limitations section, which conceded most of my opponent’s point.

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u/arne_ilunga40 points·2 years ago

Open-label extensions lose their randomisation. Anybody still enrolled at week 104 is a selected group and the numbers describe that group.

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