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c/trialwatch·submitted 5 months ago by u/plateau_patrol

someone explain FLOW to me like I have not read a paper in years

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someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial identifiers straight in a note file because I kept mixing up two programmes in the same sentence. Went looking for the registered protocol to see whether the…

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11 comments, started 5 months ago
u/yusuf_achebe35 points·5 months ago

This. Intention-to-treat versus completer analysis routinely moves the headline by several points.

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u/sanne_laurent23 points·5 months ago

Small fix — that was the cardiovascular outcomes trial, so weight was a secondary endpoint and the population was different.

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u/careful_gradient_again8 points·5 months ago

a press release is not a publication

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u/britta_boateng5 points·5 months ago·edited

a press release is not a publication

careful_gradient_again is right about the programme names. They are different populations with different endpoints.

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u/milos_trevino1 point·5 months ago

a mean is not a promise

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u/injection_site_iris1 point·5 months ago

the appendix is where the interesting tables live

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u/milos_vanhecke12 points·5 months ago

Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight.

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u/hamza_weiss7 points·5 months ago·edited

Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight.

Disagreeing with this line: that is a relative reduction and the absolute numbers are considerably less dramatic.

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u/milos_vanhecke3 points·5 months ago

registry entry, protocol, publication — three different documents

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u/adaeze_cabrera4 points·5 months ago

That is the 68-week readout, not the 72-week one. Different trial, different duration.

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u/plateau_patrolOP2 points·5 months ago

SELECT was cardiovascular outcomes, not weight

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