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c/trialwatch·submitted 5 months ago by u/plateau_patrol

someone explain FLOW to me like I have not read a paper in years

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someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial identifiers straight in a note file because I kept mixing up two programmes in the same sentence. Went looking for the registered protocol to see whether the…

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6 comments, started 5 months ago
u/tomas_kimani0 points·5 months ago

The registered protocol is public. Comparing the registered primary endpoint with the reported one is a two-minute check and it is how outcome switching gets caught.

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u/laila_almeida1 point·5 months ago

Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about.

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u/plateau_patrolOP1 point·5 months ago

How long was the randomised phase before any extension?

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u/rina_bergstrom1 point·5 months ago

STEP is semaglutide obesity, SURMOUNT is tirzepatide obesity, they are not interchangeable

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u/plateau_patrolOP1 point·5 months ago

Absolute or relative risk reduction?

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u/nikhil_lindqvist1 point·5 months ago·edited

What was the comparator?

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