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Single comment threadYou are looking at one branch of unpopular opinion: most of what gets said here about hazard ratio is guesswork — 19 comments in the full submission. View in context.
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c/trialwatch·submitted 2 months ago by u/zaid_roos

unpopular opinion: most of what gets said here about hazard ratio is guesswork

Press Releasebranch of 7 comments

unpopular opinion: most of what gets said here about hazard ratio is guesswork. Not a hot take, just something I have not seen said plainly here. A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like…

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7 comments, started 2 months ago
u/iman_castellanos14 points·2 months ago

Which trial, and which arm?

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u/sofia_ferreira9 points·2 months ago

registry entry, protocol, publication — three different documents

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u/week_four_wall10 points·2 months ago

the appendix is where the interesting tables live

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u/sofia_wikstrom6 points·2 months ago

Yes — the interval is the finding. A point estimate with a wide interval is a hypothesis in a nice font.

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u/nhs_waitlist_nUK2 points·2 months ago

This. Intention-to-treat versus completer analysis routinely moves the headline by several points.

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u/piotr_bruun8 points·2 months ago

Same. A press release is a claim about a result; the publication is the result.

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u/zaid_roosOP6 points·2 months ago

read the endpoint before you read the headline

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